Evidence map›Paper›PMID 38495707›Full record

ArticleBiomedical optics express2024

High-speed, phase contrast retinal and blood flow imaging using an adaptive optics partially confocal multi-line ophthalmoscope.

Soohyun Lee, Stacey S Choi, Ratheesh K Meleppat, Robert J Zawadzki, Nathan Doble

Abstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Soohyun LeeCollege of Optometry, The Ohio State University, 338 West 10th Avenue, Columbus, Ohio 43210, USA.ORCID https://orcid.org/0000-0002-1541-5175
Stacey S ChoiCollege of Optometry, The Ohio State University, 338 West 10th Avenue, Columbus, Ohio 43210, USA.
Ratheesh K MeleppatUC Davis Eye Center, Department of Ophthalmology and Vision Science, University of California, Davis, 4860 Y Street, Suite 2400, Sacramento, California 95817, USA.ORCID https://orcid.org/0000-0003-0240-9419
Robert J ZawadzkiUC Davis Eye Center, Department of Ophthalmology and Vision Science, University of California, Davis, 4860 Y Street, Suite 2400, Sacramento, California 95817, USA.ORCID https://orcid.org/0000-0002-9574-156X
Nathan DobleCollege of Optometry, The Ohio State University, 338 West 10th Avenue, Columbus, Ohio 43210, USA.

Funding

Full Field OCT for Cellular Level Structural and Functional Retinal ImagingR01EY031098 · NEI · OHIO STATE UNIVERSITY · PI DOBLE, NATHAN, ZAWADZKI, ROBERT J · 2020 to 2023
$2.3M
OCT-based functional biomarkers for degenerative diseases of the photoreceptor-RPE-choroid neurovascular unitR01EY034340 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Ravi S. Jonnal, Robert J Zawadzki · 2023 to 2026
$2.2M
Investigating fundamental properties and clinical applications of the optoretinogramR01EY033532 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Ravi S. Jonnal · 2022 to 2026
$2.0M
NEI NIH HHS R01 EY031098NEI NIH HHS R01 EY033532NEI NIH HHS R01 EY034340
6 · The paper itself

Abstract

High-speed, phase contrast retinal and blood flow imaging using an adaptive optics partially confocal multi-line ophthalmosocope (AO-pcMLO) is described. It allows for simultaneous confocal and phase contrast imaging with various directional multi-line illumination by using a single 2D camera and a digital micromirror device (DMD). Both vertical and horizontal line illumination directions were tested, for photoreceptor and vascular imaging. The phase contrast imaging provided improved visualization of retinal structures such as cone inner segments, vessel walls and red blood cells with images being acquired at frame rates up to 500 Hz. Blood flow velocities of small vessels (<40

Identifiers

PMID38495707
PMCPMC10942708

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.