Evidence map›Paper›PMID 38495568›Full record

ArticleArXiv2024

Transcription factor clusters as information transfer agents.

Rahul Munshi, Jia Ling, Sergey Ryabichko, Eric Wieschaus, Thomas Gregor

Open access · goldAbstract readPreprint
PubMed Full text at PMC
In one paragraph

Article in ArXiv, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 13 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Rahul MunshiJoseph Henry Laboratories of Physics, Princeton University, Princeton, NJ 08544, USA.
Jia LingLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.
Sergey RyabichkoLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.
Eric WieschausLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.
Thomas GregorJoseph Henry Laboratories of Physics, Princeton University, Princeton, NJ 08544, USA.
Princeton University · USCentre National de la Recherche Scientifique · FRHoward Hughes Medical Institute · US

Funding

The Biophysical and Molecular Mechanisms of Reliability in DevelopmentR01GM097275 · NIGMS · PRINCETON UNIVERSITY · PI GREGOR, THOMAS · 2011 to 2024
$4.9M
Control of the 4D chromatin landscape underlying gene activity during developmentU01DK127429 · NIDDK · PRINCETON UNIVERSITY · PI GREGOR, THOMAS, LEVINE, MICHAEL STEVEN · 2020 to 2024
$3.2M
Imaging chromosome dynamics and measuring its impact on transcriptional activityU01DA047730 · NIDA · PRINCETON UNIVERSITY · PI GREGOR, THOMAS, LEVINE, MICHAEL STEVEN · 2018 to 2019
$740k
NIDA NIH HHS U01 DA047730NIDDK NIH HHS U01 DK127429NIGMS NIH HHS R01 GM097275
6 · The paper itself

Abstract

Deciphering how genes interpret information from transcription factor (TFs) concentrations within the cell nucleus remains a fundamental question in gene regulation. Recent advancements have revealed the heterogeneous distribution of TF molecules, posing challenges to precisely decoding concentration signals. Using high-resolution single-cell imaging of the fluorescently tagged TF Bicoid in living

Identifiers

PMID38495568
PMCPMC10942473
OpenAlexW4392538504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.