Evidence map›Paper›PMID 38495540›Full record

ArticleJAAD international2024

Botulinum toxin A versus microwave thermolysis for primary axillary hyperhidrosis: A randomized controlled trial.

Gabriela Lladó Grove, Katrine Togsverd-Bo, Claus Zachariae, Merete Haedersdal

Abstract read
In one paragraph

Article in JAAD international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Don't Sweat It: Cannabinoid CB1 Receptors Reduce Sweating in a Mouse Model.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Review
  4. Axillary microwave thermolysis in patients with severe primary hyperhidrosis: retrospective case series.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
    Article
  5. Article
  6. Review
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gabriela Lladó GroveDepartment of Dermatology, Copenhagen University Hospital - Bispebjerg, Copenhagen, Denmark.
Katrine Togsverd-BoDepartment of Dermatology, Copenhagen University Hospital - Bispebjerg, Copenhagen, Denmark.
Claus ZachariaeDepartment of Dermatology, Copenhagen University Hospital - Gentofte, Copenhagen, Denmark.
Merete HaedersdalDepartment of Dermatology, Copenhagen University Hospital - Bispebjerg, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Botulinum toxin A (BTX) and microwave thermolysis (MWT) represent 2 treatment modalities for axillary hyperhidrosis with different procedural and efficacy profiles. Objective: To compare long-term outcomes following BTX vs MWT treatment of axillary hyperhidrosis. Methods: A prospective, randomized, within-patient, controlled trial, treating axillary hyperhidrosis with contralateral BTX and MWT. Objective sweat measurement and patient-reported outcome measures for sweat and odor were collected at baseline, 6-month and 1-year follow-up (6M/1YFU). Hair reduction and patient treatment preference was also assessed. Results: Sweat reduction was significant (all Limitations: The intrinsic challenges in efficacy assessment. Conclusion: This study exhibited BTX and MWT with similar sweat reduction, but distinguishable odor and hair reduction at 1-year FU. These findings support individualized treatment approaches for axillary hyperhidrosis based on patient-specific symptoms and preferences.

Indexed as

botulinum toxinbromhidrosishyperhidrosisindividualized treatmentmicrowave thermolysisosmidrosispersonalized therapyPROMsQoLrandomized controlled trialRCT

Identifiers

PMID38495540
PMCPMC10940128

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.