Evidence map›Paper›PMID 38495533›Full record

ArticleFrontiers in genome editing2024

Nuclease-free precise genome editing corrects MECP2 mutations associated with Rett syndrome.

Swati Bijlani, Ka Ming Pang, Lakshmi V Bugga, Sampath Rangasamy, Vinodh Narayanan, Saswati Chatterjee

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genome editing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Swati BijlaniDepartment of Surgery, Beckman Research Institute of the City of Hope, Duarte, CA, United States.
Ka Ming PangDepartment of Surgery, Beckman Research Institute of the City of Hope, Duarte, CA, United States.
Lakshmi V BuggaDepartment of Surgery, Beckman Research Institute of the City of Hope, Duarte, CA, United States.
Sampath RangasamyCenter for Rare Childhood Disorders (C4RCD), Neurogenomics Division, Translational Genomics Research Institute (TGen), Phoenix, AZ, United States.
Vinodh NarayananCenter for Rare Childhood Disorders (C4RCD), Neurogenomics Division, Translational Genomics Research Institute (TGen), Phoenix, AZ, United States.
Saswati ChatterjeeDepartment of Surgery, Beckman Research Institute of the City of Hope, Duarte, CA, United States.
Beckman Research InstituteTranslational Genomics Research Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rett syndrome is an acquired progressive neurodevelopmental disorder caused by

Indexed as

adeno-associated virusgenome editinghomologous recombinationMeCP2Rett syndrome

Identifiers

PMID38495533
PMCPMC10940404
OpenAlexW4392365254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.