Evidence map›Paper›PMID 38495509›Full record

ArticleFrontiers in microbiology2024

Genetic evidence strengthens the bidirectional connection between gut microbiota and

Jingyi Peng, Kun Cai, Guanglei Chen, Linxiao Liu, Lili Peng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Bacteriophage Therapy AgainstAntibiotics (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jingyi PengGuizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Kun CaiGuizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Guanglei ChenGuizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Linxiao LiuGuizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Lili PengThe First People's Hospital of Hangzhou Lin'an District, Hangzhou, Zhejiang, China.
Hangzhou First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In recent investigations, substantial strides have been made in the precise modulation of the gut microbiota to prevent and treat a myriad of diseases. Simultaneously, the pressing issue of widespread antibiotic resistance and multidrug resistance resulting from Materials and methods: Utilizing the aggregated summary statistics from Genome-Wide Association Studies (GWAS), we conducted Mendelian Randomization (MR) analyses encompassing 18,340 participants to explore the interplay between the gut microbiota and Results: In this study, we employed 2,818 SNPs associated with 211 species of gut microbiota as instrumental variables (IVs). Through IVW analysis, our positive MR findings revealed a significant negative correlation between the occurrence of Conclusion: In summation, the MR analysis outcomes corroborate the presence of bidirectional causal relationships between the gut microbiota and

Indexed as

antagonistic effectsgut microbiotaMendelian randomizationpathogenic bacterial colonizationShigella infections

Identifiers

PMID38495509
PMCPMC10941758
OpenAlexW4392358981

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.