Evidence map›Paper›PMID 38495395›Full record

ArticleJCEM case reports2024

An Unlikely Source of Iodine Uptake: A Bronchogenic Cyst Masquerading as Metastatic Thyroid Cancer.

Martha Dillon, Rachel Zielinski, Jennifer Worth, Melinda Sanders, Omar Ibrahim, Tarunya Vedere

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JCEM case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Martha DillonPrimary Care Internal Medicine Residency, University of Connecticut Health Center: UConn Health, Farmington, CT 06030, USA.
Rachel ZielinskiPrimary Care Internal Medicine Residency, University of Connecticut Health Center: UConn Health, Farmington, CT 06030, USA.
Jennifer WorthThoracic Surgery, Hartford Healthcare, Norwich, CT 06360, USA.
Melinda SandersPathology and Laboratory Medicine, University of Connecticut Health Center: UConn Health, Farmington, CT 06030, USA.
Omar IbrahimInterventional Pulmonology, University of Connecticut Health Center: UConn Health, Farmington, CT 06030, USA.
Tarunya VedereEndocrine Neoplasia, Endocrinology, University of Connecticut Health Center: UConn Health, Farmington, CT 06030, USA.ORCID https://orcid.org/0009-0003-7010-0998
UConn Health · USHartford Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioactive iodine therapy and posttreatment scanning are essential components of differentiated thyroid carcinoma treatment and detection of metastatic disease. False-positive results can be seen on an I-131 scan and are important for clinicians to be aware of. Here, we present a case of a 33-year-old female with follicular thyroid carcinoma who was noted to have an area of moderate uptake in the chest on a whole-body scan following remnant ablation with 30 mCi of I-131 (1.11GBq) concerning for a metastatic hilar lymph node. This was determined to be a mediastinal bronchogenic cyst on surgical pathology. It has been previously proposed that the expression of sodium iodide symporters in some bronchogenic cysts could be the mechanism by which iodine uptake is seen within them. We were able to demonstrate positive immunohistochemical staining for both sodium iodide symporter and the associated paired box gene 8 transcription factor in the cyst sample, which supports the proposed theory.

Indexed as

bronchogenic cystfollicular thyroid carcinomaradioactive iodinesodium iodide symporter

Identifiers

PMID38495395
PMCPMC10943498
OpenAlexW4392880733

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.