Evidence map›Paper›PMID 38495055›Full record

ArticleBioinformatics advances2024

CloudProteoAnalyzer: scalable processing of big data from proteomics using cloud computing.

Jiancheng Li, Yi Xiong, Shichao Feng, Chongle Pan, Xuan Guo

Abstract read
In one paragraph

Article in Bioinformatics advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. SEMQuant: Extending Sipros-Ensemble with Match-Between-Runs for Comprehensive Quantitative Metaproteomics.Bioinformatics research and applications : ... international symposium, ISBRA ... proceedings. ISBRA (Conference) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiancheng LiDepartment of Computer Science and Engineering, University of North Texas, Denton, TX 76203, United States.ORCID https://orcid.org/0009-0004-6360-225X
Yi XiongSchool of Biological Sciences, University of Oklahoma, Norman, OK 73019, United States.
Shichao FengDepartment of Computer Science and Engineering, University of North Texas, Denton, TX 76203, United States.
Chongle PanSchool of Biological Sciences, University of Oklahoma, Norman, OK 73019, United States.ORCID https://orcid.org/0000-0003-2860-0334
Xuan GuoDepartment of Computer Science and Engineering, University of North Texas, Denton, TX 76203, United States.

Funding

Proteomic Stable Isotope Probing as a Novel Approach for Linking Prebiotics with Active Gut MicrobiotaR01AT011618 · NCCIH · UNIVERSITY OF OKLAHOMA · PI PAN, CHONGLE · 2021 to 2025
$1.8M
A Computational Framework for Protein Identification and Quantification in Metaproteomics Using Data-Independent AcquisitionR15LM013460 · NLM · UNIVERSITY OF NORTH TEXAS · PI GUO, XUAN · 2020 to 2020
$361k
NCCIH NIH HHS R01 AT011618NLM NIH HHS R15 LM013460
6 · The paper itself

Abstract

Summary: Shotgun proteomics is widely used in many system biology studies to determine the global protein expression profiles of tissues, cultures, and microbiomes. Many non-distributed computer algorithms have been developed for users to process proteomics data on their local computers. However, the amount of data acquired in a typical proteomics study has grown rapidly in recent years, owing to the increasing throughput of mass spectrometry and the expanding scale of study designs. This presents a big data challenge for researchers to process proteomics data in a timely manner. To overcome this challenge, we developed a cloud-based parallel computing application to offer end-to-end proteomics data analysis software as a service (SaaS). A web interface was provided to users to upload mass spectrometry-based proteomics data, configure parameters, submit jobs, and monitor job status. The data processing was distributed across multiple nodes in a supercomputer to achieve scalability for large datasets. Our study demonstrated SaaS for proteomics as a viable solution for the community to scale up the data processing using cloud computing. Availability and implementation: This application is available online at https://sipros.oscer.ou.edu/ or https://sipros.unt.edu for free use. The source code is available at https://github.com/Biocomputing-Research-Group/CloudProteoAnalyzer under the GPL version 3.0 license.

Identifiers

PMID38495055
PMCPMC10942798

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.