Evidence map›Paper›PMID 38494840›Full record

ReviewJournal of cellular and molecular medicine2024

Research progress on the roles of dopamine and dopamine receptors in digestive system diseases.

Xianmin Lu, Qi Liu, Ya Deng, Jiangbo Wu, Xingyi Mu, Xiaoxu Yang, Ting Zhang, Chen Luo, Zhuo Li, Siqi Tang and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Sex- and Age-Related Differences in Physiological [Bioengineering (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Cancer and neurotransmitter receptors.Chinese medical journal · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Xianmin LuDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Qi LiuDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Ya DengDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Jiangbo WuDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.ORCID 0000-0001-7926-6431
Xingyi MuDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Xiaoxu YangDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Ting ZhangDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Chen LuoDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zhuo LiDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Siqi TangDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.ORCID 0000-0002-6101-4348
Yanxia HuDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Qian DuDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Jingyu XuDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.ORCID 0000-0002-0545-0444
Rui XieDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zunyi Medical University · CN

Funding

Collaborative Innovation Center of Chinese Ministry of Education 2020-39The Science and Technology Plan Project of Guizhou Province QIANKEHEJICHU-ZK(2023)YIBAN556This study was supported by Graduate Education and Teaching Innovation Program of Zunyi Medical University ZYK163This study was supported by Key Projects of Guizhou Provincial Basic Research Program QIAN KE HE JI CHU-ZK (2021) ZHONG DIAN 004This study was supported by research grants the National Natural Science Foundation of China 31960151This study was supported by research grants the National Natural Science Foundation of China 32160208This study was supported by research grants the National Natural Science Foundation of China 81660099This study was supported by research grants the National Natural Science Foundation of China 81770610This study was supported by research grants the National Natural Science Foundation of China 81970541This study was supported by research grants the National Natural Science Foundation of China 82170628This study was supported by the Outstanding Scientific Youth Fund of Guizhou Province Qian Ke He Platform Talents [2021] 5647This study was supported by Zunyi Science and Technology Bureau (Outstanding Young Talents in Zunyi City 2020-1
6 · The paper itself

Abstract

Dopamine (DA) is a neurotransmitter synthesized in the human body that acts on multiple organs throughout the body, reaching them through the blood circulation. Neurotransmitters are special molecules that act as messengers by binding to receptors at chemical synapses between neurons. As ligands, they mainly bind to corresponding receptors on central or peripheral tissue cells. Signalling through chemical synapses is involved in regulating the activities of various body systems. Lack of DA or a decrease in DA levels in the brain can lead to serious diseases such as Parkinson's disease, schizophrenia, addiction and attention deficit disorder. It is widely recognized that DA is closely related to neurological diseases. As research on the roles of brain-gut peptides in human physiology and pathology has deepened in recent years, the regulatory role of neurotransmitters in digestive system diseases has gradually attracted researchers' attention, and research on DA has expanded to the field of digestive system diseases. This review mainly elaborates on the research progress on the roles of DA and DRs related to digestive system diseases. Starting from the biochemical and pharmacological properties of DA and DRs, it discusses the therapeutic value of DA- and DR-related drugs for digestive system diseases.

Indexed as

Digestive System DiseasesParkinson DiseaseDopamineHumansNeurotransmitter AgentsReceptors, DopamineDopamineNeurotransmitter AgentsReceptors, Dopaminebrain-gut axisdopaminedopamine receptorliver cancerneurotransmitter

Identifiers

PMID38494840
PMCPMC10945074
OpenAlexW4392922214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.