Evidence map›Paper›PMID 38494585›Full record

ReviewInternational urology and nephrology2024

Research progress of astragaloside IV in treating acute kidney injury.

Yu Liu, Youqun Huang, Dongxuan Sun, Naijing Ye, Tong Chen, Mengfan Yang, Li Zhou, Hequn Zou

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Research Progress on Chemical Components ofMolecules (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yu LiuDepartment of Nephrology, Health Science Center, South China Hospital, Shenzhen University, No.1, Fuxin Road, Longgang District, Shenzhen, People's Republic of China.
Youqun Huang *Department of Nephrology, Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, Sichuan, China.
Dongxuan Sun *Department of Nephrology, Health Science Center, South China Hospital, Shenzhen University, No.1, Fuxin Road, Longgang District, Shenzhen, People's Republic of China.
Naijing YeDepartment of Nephrology, Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, Sichuan, China.
Tong ChenDepartment of Nephrology, Health Science Center, South China Hospital, Shenzhen University, No.1, Fuxin Road, Longgang District, Shenzhen, People's Republic of China.
Mengfan YangDepartment of Nephrology, Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, Sichuan, China.
Li ZhouDepartment of Nephrology, Health Science Center, South China Hospital, Shenzhen University, No.1, Fuxin Road, Longgang District, Shenzhen, People's Republic of China.
Hequn ZouThe Chinese University of Hong Kong, No. 2001, Longxiang Avenue, Shenzhen, Guangdong, China. zhqshenzhendaxue@163.com.
Shenzhen University Health Science Center · CNChengdu University of Traditional Chinese Medicine · CNChinese University of Hong Kong, Shenzhen · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is one of the most common clinical critical illnesses, with decreased glomerular filtration rate, retention of nitrogen products, water and electrolyte disorders, and acid-base imbalance as the main clinical manifestations. Presently, there is no effective treatment for acute kidney injury, but the main treatment is to cure the primary disease, remove risk factors, maintain acid-base and water-electrolyte balance, and undergo kidney replacement. However, the mortality rate is still high. Investigations and studies showed that the mortality rate of patients with acute kidney injury in the ICU is 5-80% [1]. In recent years, Chinese medicine has been widely used in acute kidney injury treatment due to its complete dialectical system and rich experience. Astragalus is a commonly used medicine in traditional Chinese medicine to treat acute kidney injury. Astragaloside IV is the main active component of traditional Chinese medicine, Astragalus membranaceus. This article summarizes the relevant studies on treating acute kidney injury with astragaloside IV.

Indexed as

Acute Kidney InjurySaponinsTriterpenesDrugs, Chinese HerbalHumansastragaloside ADrugs, Chinese HerbalSaponinsTriterpenesAcute kidney injuryAstragaloside IVAstragalus

Identifiers

PMID38494585
OpenAlexW4392923949

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.