Evidence map›Paper›PMID 38494492›Full record

ArticleJournal of translational medicine2024

Development and validation of predictive models for myopia onset and progression using extensive 15-year refractive data in children and adolescents.

Jing Zhao, Yanze Yu, Yiming Li, Feng Li, Zhe Zhang, Weijun Jian, Zhi Chen, Yang Shen, Xiaoying Wang, Zhengqiang Ye and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The application of artificial intelligence in myopia prediction for children and adolescents: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  4. Artificial intelligence in pediatric myopia - a narrative review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
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  15. IMI-Interventions for Controlling Myopia Onset and Progression 2025.Investigative ophthalmology & visual science · 2025
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Cross-population validation of the PreMO risk indicator for predicting myopia onset in children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Jing Zhao *Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Yanze Yu *Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Yiming Li *Department of Research Collaboration, R&D Center. Beijing Deepwise & League of PHD Technology Co, Ltd., Beijing, 100080, China.
Feng LiDepartment of Research Collaboration, R&D Center. Beijing Deepwise & League of PHD Technology Co, Ltd., Beijing, 100080, China.
Zhe ZhangDepartment of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Weijun JianDepartment of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Zhi ChenDepartment of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Yang ShenDepartment of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Xiaoying WangDepartment of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Zhengqiang YeInformation Center, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.
Chencui HuangDepartment of Research Collaboration, R&D Center. Beijing Deepwise & League of PHD Technology Co, Ltd., Beijing, 100080, China. huangchencui@deepwise.com.
Xingtao ZhouDepartment of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China. doctzhouxingtao@163.com.ORCID 0000-0002-3465-1579
Chinese Academy of Medical Sciences & Peking Union Medical College · CNCenter for High Pressure Science & Technology Advanced Research · CNEye & ENT Hospital of Fudan University · CN

Funding

Healthy Young Talents Project of Shanghai Municipal Health Commission 2022YQ015National Natural Science Foundation of China 82271119Project of Shanghai Science and Technology 20410710100Project of Shanghai Science and Technology 21Y11909800Science and Technology Commission of Fengxian District, Shanghai Municipality 2020-015Shanghai Rising-Star Program 23QA1401000
6 · The paper itself

Abstract

backgroundGlobal myopia prevalence poses a substantial public health burden with vision-threatening complications, necessitating effective prevention and control strategies. Precise prediction of spherical equivalent (SE), myopia, and high myopia onset is vital for proactive clinical interventions.

methodsWe reviewed electronic medical records of pediatric and adolescent patients who underwent cycloplegic refraction measurements at the Eye & Ear, Nose, and Throat Hospital of Fudan University between January 2005 and December 2019. Patients aged 3-18 years who met the inclusion criteria were enrolled in this study. To predict the SE and onset of myopia and high myopia in a specific year, two distinct models, random forest (RF) and the gradient boosted tree algorithm (XGBoost), were trained and validated based on variables such as age at baseline, and SE at various intervals. Outputs included SE, the onset of myopia, and high myopia up to 15 years post-initial examination. Age-stratified analyses and feature importance assessments were conducted to augment the clinical significance of the models.

resultsThe study enrolled 88,250 individuals with 408,255 refraction records. The XGBoost-based SE prediction model consistently demonstrated robust and better performance than RF over 15 years, maintaining an R

conclusionsThe XGBoost predictive models exhibited high accuracy in predicting SE, onset of myopia, and high myopia among children and adolescents aged 3-18 years. Our findings emphasize the importance of early and regular examinations at a young age for predicting high myopia, thereby providing valuable insights for clinical practice.

Indexed as

MyopiaRefraction, OcularAdolescentChildChild, PreschoolHumansCycloplegic refractionHigh myopiaMachine learningMyopiaPredictive model

Identifiers

PMID38494492
PMCPMC10946190
OpenAlexW4392895558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.