Evidence map›Paper›PMID 38494464›Full record

ArticleAging clinical and experimental research2024

Bone health status evaluation in men by means of REMS technology.

Adami Giovanni, Brandi Maria Luisa, Caffarelli Carla, Casciaro Ernesto, Conversano Francesco, Di Paola Marco, Fassio Angelo, Gatti Davide, Giusti Francesca, Gonnelli Stefano and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Aging clinical and experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Pro-Osteogenic Effect of the Nutraceutical BlastiMin ComplexInternational journal of molecular sciences · 2024
    Trial
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  4. Demographic determinants of REMS-derived BMD and fragility score.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  5. Comparative longitudinal assessment of bone mineral density measured with radiofrequency echographic multi-spectrometry (REMS) and dual X-ray absorptiometry (DXA) in a cohort of peritoneal dialysis patients.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  6. Radiofrequency Echographic Multi Spectrometry (REMS) for the evaluation of bone health in systemic lupus erythematosus (SLE).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Adami Giovanni *Department of Medicine, Rheumatology Unit, University of Verona, Verona, Italy.
Brandi Maria Luisa *Italian Bone Disease Research Foundation (FIRMO), Florence, Italy.
Caffarelli Carla *Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico Le Scotte, Siena, Italy.
Casciaro Ernesto *Institute of Clinical Physiology, National Research Council, Lecce, Italy.
Conversano Francesco *Institute of Clinical Physiology, National Research Council, Lecce, Italy.
Di Paola Marco *Institute of Clinical Physiology, National Research Council, Lecce, Italy.
Fassio Angelo *Department of Medicine, Rheumatology Unit, University of Verona, Verona, Italy.
Gatti Davide *Department of Medicine, Rheumatology Unit, University of Verona, Verona, Italy.
Giusti Francesca *Donatello Bone Clinic, Villa Donatello Hospital, Sesto Fiorentino, Florence, Italy.
Gonnelli Stefano *Department of Medicine, Surgery and Neuroscience, University of Siena, Policlinico Le Scotte, Siena, Italy.
Lombardi Fiorella Anna *Institute of Clinical Physiology, National Research Council, Lecce, Italy.
Muratore Maurizio *ASL-LE, Ospedale Vito Fazzi, Lecce, Italy.
Pisani Paola *Institute of Clinical Physiology, National Research Council, Lecce, Italy. pisanipaolaifc@gmail.com.
Rossini MaurizioDepartment of Medicine, Rheumatology Unit, University of Verona, Verona, Italy.
National Research Council · ITUniversity of Verona · ITUniversity of Siena · ITFratelli Alinari (Italy) · ITOspedale Vito Fazzi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoporosis in males is largely under-diagnosed and under-treated, with most of the diagnosis confirmed only after an osteoporotic fracture. Therefore, there is an urgent need for highly accurate and precise technologies capable of identifying osteoporosis earlier, thereby avoiding complications from fragility fractures.

aimsThis study aimed to evaluate the diagnostic accuracy and precision of the non-ionizing technology Radiofrequency Echographic Multi Spectrometry (REMS) for the diagnosis of osteoporosis in a male population in comparison with conventional Dual-energy X-ray Absorptiometry (DXA).

methodsA cohort of 603 Caucasian males aged between 30 and 90 years were involved in the study. All the enrolled patients underwent lumbar and femoral scans with both DXA and REMS. The diagnostic agreement between REMS and DXA-measured BMD was expressed by Pearson correlation coefficient and Bland-Altman method. The accuracy of the diagnostic classification was evaluated by the assessment of sensitivity and specificity considering DXA as reference.

resultsA significant correlation between REMS- and DXA-measured T-score values (r = 0.91, p < 0.0001) for lumbar spine and for femoral neck (r = 0.90, p < 0.0001) documented the substantial equivalence of the two measurement techniques. Bland-Altman outcomes showed that the average difference in T-score measurement is very close to zero (-0.06 ± 0.60 g/cm

conclusionREMS, is a reliable technology for the diagnosis of osteoporosis also in men. This evidence corroborates its high diagnostic performance already observed in previous studies involving female populations.

Indexed as

OsteoporosisOsteoporotic FracturesAgedAged, 80 and overBone DensityFemaleFemur NeckHumansMaleSpectrum AnalysisBone fragilityBone health statusMenOsteoporosisRadiofrequency Echographic Multi-SpectrometryREMS

Identifiers

PMID38494464
PMCPMC10944810
OpenAlexW4392923551

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.