Evidence map›Paper›PMID 38494346›Full record

ArticlePain management nursing : official journal of the American Society of Pain Management Nurses2024

The Problem of Pain in Lupus: Epidemiological Profiles of Patients Attending Multidisciplinary Pain Clinics.

Tiffany E Jiang, Alissa P Pascual, Nathan Le, Thy B Nguyen, Sean Mackey, Beth D Darnall, Julia F Simard, Titilola Falasinnu

Open access · greenAbstract read
In one paragraph

Article in Pain management nursing : official journal of the American Society of Pain Management Nurses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tiffany E JiangDepartment of Epidemiology and Population Sciences, Stanford University School of Medicine, Stanford, CA.
Alissa P PascualDepartment of Human Biology, Stanford University, Stanford, CA.
Nathan LeUniversity of California, Los Angeles, CA.
Thy B NguyenDepartment of Epidemiology and Population Sciences, Stanford University School of Medicine, Stanford, CA.
Sean MackeyDepartments of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine Stanford, CA; Department of Neurology, Stanford University School of Medicine, Stanford, CA.
Beth D DarnallDepartments of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine Stanford, CA; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA.
Julia F SimardDepartment of Epidemiology and Population Sciences, Stanford University School of Medicine, Stanford, CA; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA; Departments of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA.
Titilola FalasinnuDepartments of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine Stanford, CA; Departments of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA. Electronic address: tof@stanford.edu.
Stanford Medicine · USStanford University · USUniversity of California, Los Angeles · US

Funding

Interdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2M
Can hydroxychloroquine prevent preeclampsia and preterm delivery in lupus pregnancy?R01AR077103 · NIAMS · STANFORD UNIVERSITY · PI SIMARD, JULIA F · 2020 to 2024
$2.4M
Research and Mentoring in Innovative Patient Oriented Pain and Opioid ScienceK24DA053564 · NIDA · STANFORD UNIVERSITY · PI Beth Denise Darnall · 2021 to 2026
$1.0M
Characterization of Chronic Pain and its Biopsychosocial Mechanisms in Lupus using Electronic Health RecordsK01AR079039 · NIAMS · STANFORD UNIVERSITY · PI FALASINNU, TITILOLA · 2021 to 2025
$631k
Mentoring in Discovery and Validation of Clinical Chronic Pain BiomarkersK24NS126781 · NINDS · STANFORD UNIVERSITY · PI MACKEY, SEAN C · 2021 to 2021
$324k
NIAMS NIH HHS K01 AR079039NIAMS NIH HHS R01 AR077103NIDA NIH HHS K24 DA053564NIDA NIH HHS T32 DA035165NINDS NIH HHS K24 NS126781
6 · The paper itself

Abstract

introductionPatients with systemic lupus erythematosus (SLE) bear a significant burden of pain. We aimed to identify factors that distinguish patients with SLE referred to comprehensive pain clinics and those who are not. Characterizing this patient population will identify unmet needs in SLE management and inform efforts to improve pain care in rheumatology.

methodsAmong patients with SLE with ≥2 rheumatology clinic visits in a large hospital system from 1998 to 2023 (n = 1319), we examined factors that distinguished those who had at least one visit to multidisciplinary pain clinics (n = 77, 5.8%) from those who did not have any visits (n = 1242, 94.2%) with a focus on biopsychosocial and socioeconomic characteristics. We extracted demographic data and ICD-9/ICD-10 codes from the EHR.

resultsPatients with SLE attending the pain clinics exhibited characteristics including average older age (mean age ± SD: 54.1 ± 17.9 vs. 48.4 ± 19.9), a higher likelihood of relying on public health insurance (50.7% vs. 34.2%), and a greater representation of Black patients (9.1% vs. 4.4%) compared to SLE patients not seen in pain clinics. Nearly all patients seen at the pain clinics presented with at least one chronic overlapping pain condition (96.1% vs. 58.6%), demonstrated a higher likelihood of having a mental health diagnosis (76.7% vs. 42.4%), and exhibited a greater number of comorbidities (mean ± SD: 6.0 ± 3.0 vs. 2.9 ± 2.6) compared to those not attending the pain clinic.

conclusionWe found notable sociodemographic and clinical differences between these patient populations. Patients presenting with multiple comorbidities might benefit from further pain screening and referral to pain clinics to provide comprehensive care, and earlier referral could mitigate the development and progression of multimorbidities.

Indexed as

Lupus Erythematosus, SystemicPain ClinicsAdultAgedFemaleHumansMaleMiddle AgedPainPain Management

Identifiers

PMID38494346
PMCPMC11144551
OpenAlexW4392888918

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.