Evidence map›Paper›PMID 38494199›Full record

ArticleRenal failure2024

Magnesium hydride protects against acetaminophen-induced acute kidney injury by inhibiting TXNIP/NLRP3/nf-κb pathway.

Yachen Si, Lulu Liu, Yinyin Zhang, Hongxia Li, Tingting Zhao, Su Liu, Xuejun Sun, Jin Cheng, Hongtao Lu

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yachen SiDepartment of Internal Medicine, No. 944 Hospital of Joint Logistics Support Force, Jiuquan, China.
Lulu LiuDepartment of Nephrology, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China.
Yinyin ZhangDepartment of Naval Medicine, Naval Medical University, Shanghai, China.
Hongxia LiDepartment of Naval Medicine, Naval Medical University, Shanghai, China.
Tingting ZhaoDepartment of Nephrology, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China.
Su LiuDepartment of Naval Medicine, Naval Medical University, Shanghai, China.
Xuejun SunDepartment of Naval Medicine, Naval Medical University, Shanghai, China.
Jin ChengInternal Medicine III (Nephrology and Endocrinology), Naval Medical Center, Naval Medical University, Shanghai, China.
Hongtao LuDepartment of Naval Medicine, Naval Medical University, Shanghai, China.
Changhai Hospital · CNSecond Military Medical University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acetaminophen (APAP)-induced acute kidney injury (APAP-AKI) has turned into one of reasons for clinic obtained renal insufficiency. Magnesium hydride (MgH

Indexed as

Acute Kidney InjuryChemical and Drug Induced Liver InjuryAcetaminophenAnimalsMagnesiumMiceNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinOxidative StressAcetaminophenMagnesiumNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinAcetaminophenacute kidney injuryapoptosisinflammationmagnesium hydrideoxidative stress

Identifiers

PMID38494199
PMCPMC10946266
OpenAlexW4394767662

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.