Evidence map›Paper›PMID 38493446›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2024

Contouring aid tools in radiotherapy. Smoothing: the false friend.

Jordi Marruecos Querol, Diego Jurado-Bruggeman, Anna Lopez-Vidal, Ricard Mesía Nin, Jordi Rubió-Casadevall, Maria Buxó, Aranzazu Eraso Urien

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Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jordi Marruecos QuerolRadiation Oncology Department, Catalan Institute of Oncology, Girona, Spain. jmarruecos@iconcologia.net.ORCID http://orcid.org/0000-0003-1405-0036
Diego Jurado-BruggemanResearch Group in Radiation Oncology and Medical Physics of Girona, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.
Anna Lopez-VidalMedical Oncology Department, Catalan Institute of Oncology, Girona, Spain.
Ricard Mesía NinMedical Oncology Department, Catalan Institute of Oncology, B-ARGO Group, IGTP, Badalona, Spain.
Jordi Rubió-CasadevallMedical Oncology Department, Catalan Institute of Oncology, Girona, Spain.
Maria BuxóGirona Biomedical Research Institute (IDIBGI), Girona, Spain.
Aranzazu Eraso UrienRadiation Oncology Department, Catalan Institute of Oncology, Girona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveContouring accuracy is critical in modern radiotherapy. Several tools are available to assist clinicians in this task. This study aims to evaluate the performance of the smoothing tool in the ARIA system to obtain more consistent volumes.

methodsEleven different geometric shapes were delineated in ARIA v15.6 (Sphere, Cube, Square Prism, Six-Pointed Star Prism, Arrow Prism, And Cylinder and the respective volumes at 45° of axis deviation (_45)) in 1, 3, 5, 7, and 10 cm side or diameter each. Post-processing drawing tools to smooth those first-generated volumes were applied in different options (2D-ALL vs 3D) and grades (1, 3, 5, 10, 15, and 20). These volumetric transformations were analyzed by comparing different parameters: volume changes, center of mass, and DICE similarity coefficient index. Then we studied how smoothing affected two different volumes in a head and neck cancer patient: a single rounded node and the volume delineating cervical nodal areas.

resultsNo changes in data were found between 2D-ALL or 3D smoothing. Minimum deviations were found (range from 0 to 0.45 cm) in the center of mass. Volumes and the DICE index decreased as the degree of smoothing increased. Some discrepancies were found, especially in figures with cleft and spikes that behave differently. In the clinical case, smoothing should be applied only once throughout the target delineation process, preferably in the largest volume (PTV) to minimize errors.

conclusionSmoothing is a good tool to reduce artifacts due to the manual delineation of radiotherapy volumes. The resulting volumes must be always carefully reviewed.

Indexed as

Head and Neck NeoplasmsRadiotherapy Planning, Computer-AssistedHumansImaging, Three-DimensionalRadiotherapy DosageTomography, X-Ray ComputedContouringDelineationRadiotherapySmoothing

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.