ArticleNPJ Parkinson's disease2024
Advanced brain aging in Parkinson's disease with cognitive impairment.
Article in NPJ Parkinson's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 11 citations in OpenAlex.
- Differential cerebral white matter tract alterations in generalized anxiety disorder revealed by ultra-high-field 7 T diffusion-weighted imaging.Journal of affective disorders · 2026Article
- Volume Alterations in Thalamic Subnuclei in Parkinson's Disease Dementia and Machine Learning-Based Prediction of Diagnosis and Severity.Brain and behavior · 2026Article
- Aging beyond diagnosis: the MRI brain age gap across disorders.GeroScience · 2026Review
- [Research progress on intelligent brain age prediction methods in diagnosis of Parkinson's disease].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026Review
- Accelerated brain aging in amyotrophic lateral sclerosis and its prognostic associations: a cohort study.BMC medicine · 2026Article
- Exercise suppresses apoptosis for alleviating Parkinson's disease: effects on pathophysiological molecular pathways.Frontiers in aging neuroscience · 2026Review
- Brain age gap as predictor of disease progression in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Cortical volumetry and longitudinal cognitive changes in Parkinson's disease: insights from the COPPADIS cohort.Brain imaging and behavior · 2025Article
- Periventricular diffusivity reflects APOE ε4-modulated amyloid accumulation and cognitive impairment in the Alzheimer's disease continuum.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Advanced brain aging, selective vulnerability in gray matter, and cognition in Parkinson's disease.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Buffering brain aging: education moderates language impairment in Parkinson's disease.Frontiers in cellular neuroscience · 2025Article
- Analysis of Brain Age Gap across Subject Cohorts and Prediction Model Architectures.Biomedicines · 2024Article
- Superpixel-ComBat modeling: A joint approach for harmonization and characterization of inter-scanner variability in T1-weighted images.Imaging neuroscience (Cambridge, Mass.) · 2024Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Patients with Parkinson's disease and cognitive impairment (PD-CI) deteriorate faster than those without cognitive impairment (PD-NCI), suggesting an underlying difference in the neurodegeneration process. We aimed to verify brain age differences in PD-CI and PD-NCI and their clinical significance. A total of 94 participants (PD-CI, n = 27; PD-NCI, n = 34; controls, n = 33) were recruited. Predicted age difference (PAD) based on gray matter (GM) and white matter (WM) features were estimated to represent the degree of brain aging. Patients with PD-CI showed greater GM-PAD (7.08 ± 6.64 years) and WM-PAD (8.82 ± 7.69 years) than those with PD-NCI (GM: 1.97 ± 7.13, P
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.