Evidence map›Paper›PMID 38492205›Full record

ReviewBreast cancer (Tokyo, Japan)2025

Liquid biopsy for breast cancer and other solid tumors: a review of recent advances.

Hirofumi Ohmura, Fumiyasu Hanamura, Yuta Okumura, Yuki Ando, Takaaki Masuda, Koshi Mimori, Koichi Akashi, Eishi Baba

Abstract readReview
PubMed Publisher
In one paragraph

Review in Breast cancer (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Breast Cancer: Extracellular Matrix and Microbiome Interactions.International journal of molecular sciences · 2024
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hirofumi OhmuraDepartment of Oncology and Social Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Fumiyasu HanamuraDepartment of Internal Medicine, Kyushu University Beppu Hospital, Oita, Japan.
Yuta OkumuraDepartment of Internal Medicine, Kyushu University Beppu Hospital, Oita, Japan.
Yuki AndoDepartment of Surgery, Kyushu University Beppu Hospital, Oita, Japan.
Takaaki MasudaDepartment of Surgery, Kyushu University Beppu Hospital, Oita, Japan.
Koshi MimoriDepartment of Surgery, Kyushu University Beppu Hospital, Oita, Japan.
Koichi AkashiDepartment of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Eishi BabaDepartment of Oncology and Social Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan. baba.eishi.889@m.kyushu-u.ac.jp.ORCID http://orcid.org/0000-0001-9428-6772
Kyushu University Beppu Hospital · JPKyushu University · JPNational Hospital Organization Kyushu Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liquid biopsy using circulating tumor DNA (ctDNA) has been reported to be less invasive and effective for comprehensive genetic analysis of heterogeneous solid tumors, including decision-making for therapeutic strategies, predicting recurrence, and detecting genetic factors related to treatment resistance in various types of cancers. Breast cancer, colorectal cancer, and lung cancer are among the most prevalent malignancies worldwide, and clinical studies of liquid biopsy for these cancers are ongoing. Liquid biopsy has been used as a companion diagnostic tool in clinical settings, and research findings have accumulated, especially in cases of colorectal cancer after curative resection and non-small cell lung cancer (NSCLC) after curative chemoradiotherapy, in which ctDNA detection helps predict eligibility for adjuvant chemotherapy. Liquid biopsy using ctDNA shows promise across a wide range of cancer types, including breast cancer, and its clinical applications are expected to expand further through ongoing research. In this article, studies on liquid biopsy in breast cancer, colorectal cancer, and NSCLC are compared focusing on ctDNA.

Indexed as

Biomarkers, TumorBreast NeoplasmsCirculating Tumor DNACarcinoma, Non-Small-Cell LungColorectal NeoplasmsFemaleHumansLiquid BiopsyLung NeoplasmsBiomarkers, TumorCirculating Tumor DNABreast cancerColorectal cancerctDNALiquid biopsyLung cancer

Identifiers

PMID38492205
OpenAlexW4392880755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.