Evidence map›Paper›PMID 38492093›Full record

ArticleAging clinical and experimental research2024

Association of Mediterranean diet adherence with disease progression, quality of life and physical activity, sociodemographic and anthropometric parameters, and serum biomarkers in community-dwelling older adults with multiple sclerosis: a cross-sectional study.

Christina Tryfonos, Maria Chrysafi, Sousana K Papadopoulou, Konstantinos Vadikolias, Maria Spanoudaki, Maria Mentzelou, Dimitrios Fotiou, Eleni Pavlidou, Georgios Gkouvas, Theofanis Vorvolakos and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Aging clinical and experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Christina TryfonosDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400, Lemnos, Myrina, Greece.
Maria ChrysafiDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400, Lemnos, Myrina, Greece.
Sousana K PapadopoulouDepartment of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, Thessaloniki, Greece.
Konstantinos VadikoliasDepartment of Neurology, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
Maria SpanoudakiDepartment of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, Thessaloniki, Greece.
Maria MentzelouDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400, Lemnos, Myrina, Greece.
Dimitrios FotiouDepartment of Neurology, School of Medicine, Aristoteleio University of Thessaloniki, Thessaloníki, Greece.
Eleni PavlidouDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400, Lemnos, Myrina, Greece.
Georgios GkouvasClinical Dietetics and Nutritional Department, 424 General Military Hospital, Thessaloníki, Greece.
Theofanis VorvolakosDepartment of Geriatric Psychiatry, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
Apostolos Michailidis1st Department of Pathology, 424 General Military Hospital, Thessaloníki, Greece.
Alexia BisbinasUniversity General Hospital of Thessaloniki AHEPA, Thessaloníki, Greece.
Olga AlexatouDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400, Lemnos, Myrina, Greece.
Constantinos GiaginisDepartment of Food Science and Nutrition, School of Environment, University of the Aegean, 81400, Lemnos, Myrina, Greece. cgiaginis@aegean.gr.ORCID http://orcid.org/0000-0003-2878-4831
University of the Aegean · GR424 General Military Hospital · GRDemocritus University of Thrace · GRInternational Hellenic University · GRAHEPA University Hospital · GRAristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple sclerosis (MS) constitutes a chronic inflammatory and degenerative demyelinating disease, which can progressively lead to a broad range of sensorimotor, cognitive, visual, and autonomic function symptoms, independently of patient' age. However, the clinical studies that examine the role of dietary patterns against disease progression and symptomatology remain extremely scarce, especially concerning Mediterranean diet (MD) in the subgroup age of older adults with MS.

aimsThe present study aimed to investigate the potential impact of MD compliance in disease progression and symptoms severity as well as quality of life and physical activity of community-dwelling older adults with MS.

methodsThis is a cross-sectional conducted on 227 older adults with no history of other severe disease. Relevant questionnaires were applied to collect sociodemographic and anthropometric factors by face-to face interviews between patients and qualified personnel. Serum biomarkers were retrieved by patients' medical records.

resultsHigher MD compliance was independently associated with younger patients' age, lower risk of overweight/obesity and abdominal obesity, decreased disease progression and higher muscle mass, as well as greater physical activity, better quality of life, and adequate serum ferritin and albumin levels

conclusionsMD may exert beneficial effects in older adults with MS. Future strategies and policies are highly recommended to inform both the general population and the older patients with MS for the beneficial effects of MD in preventing MS and in improving or even slowing down the disease progression and symptoms severity of MS.

Indexed as

Diet, MediterraneanMultiple SclerosisAgedBiomarkersCross-Sectional StudiesDisease ProgressionExerciseHumansIndependent LivingObesityQuality of LifeBiomarkersDisease progressionMediterranean dietMultiple sclerosisOlder adultsQuality of lifeSymptoms

Identifiers

PMID38492093
PMCPMC10944396
OpenAlexW4392880957

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.