Evidence map›Paper›PMID 38492045›Full record

ArticlePediatric radiology2024

Predicting event-free survival after induction of remission in high-risk pediatric neuroblastoma: combining

Lijuan Feng, Xu Yang, Chao Wang, Hui Zhang, Wei Wang, Jigang Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Characteristics and prognostic value of pre-treatmentEuropean journal of nuclear medicine and molecular imaging · 2026
    Observational
  3. Article
  4. [Analysis of induction therapy response in children with high-risk neuroblastoma].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Article
  5. Observational
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lijuan FengDepartment of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing, 100050, China.ORCID 0000-0002-2173-8210
Xu YangDepartment of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing, 100050, China.
Chao WangSinoUnion Healthcare Inc, Beijing, China.
Hui ZhangDepartment of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Wei WangDepartment of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing, 100050, China.
Jigang YangDepartment of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing, 100050, China. yangjigang@ccmu.edu.cn.ORCID 0000-0002-0538-7676
Capital Medical University · CNTsinghua University · CN

Funding

National Natural Science Foundation of China 82102088National Natural Science Foundation of China 82272034
6 · The paper itself

Abstract

backgroundAccurately quantifying event-free survival after induction of remission in high-risk neuroblastoma can lead to better subsequent treatment decisions, including whether more aggressive therapy or milder treatment is needed to reduce unnecessary treatment side effects, thereby improving patient survival.

objectiveTo develop and validate a MATERIALS AND

methodsOne hundred and seventy-two patients with high-risk neuroblastoma who underwent an

resultsThe Curie score had the lowest efficacy for the assessment of event-free survival, with a C-index of 0.576 and 0.553 in the training and validation cohorts, respectively. The radiomics model, constructed from 11 radiomics features, outperformed the clinical model in predicting event-free survival in both the training cohort (C-index, 0.780 vs. 0.653) and validation cohort (C-index, 0.687 vs. 0.667). The nomogram predicted the best prognosis for event-free survival in both the training and validation cohorts, with C-indices of 0.819 and 0.712, and 1-year areas under the curve of 0.899 and 0.748, respectively.

conclusion

Indexed as

NeuroblastomaNomogramsRemission Induction3-IodobenzylguanidineChildChild, PreschoolDisease-Free SurvivalFemaleHumansInfantMalePredictive Value of TestsRadiomicsRadiopharmaceuticalsRetrospective StudiesSingle Photon Emission Computed Tomography Computed Tomography3-IodobenzylguanidineRadiopharmaceuticalsChildEvent-free survivalNeuroblastomaPrognosisRadiomicsSingle-photon emission computed tomography-computed tomography

Identifiers

PMID38492045
OpenAlexW4392885563

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.