Evidence map›Paper›PMID 38491819›Full record

ArticleCancer medicine2024

Notch signaling genes and CD8

Kazuhiro Ogi, Takahiro Iwamoto, Takashi Sasaya, Koyo Nishiyama, Takaaki Tokura, Takanori Sasaki, Hironari Dehari, Yohei Arihara, Kazuyuki Murase, Masato Saito and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Notch signaling genes and CD8Cancer medicine · 2024
    Article
  7. Frontiers in pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Kazuhiro OgiDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.ORCID 0000-0002-0104-9223
Takahiro IwamotoDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Takashi SasayaDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Koyo NishiyamaDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Takaaki TokuraDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Takanori SasakiDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Hironari DehariDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Yohei AriharaDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Kazuyuki MuraseDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Masato SaitoDepartment of Radiology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Masanori SomeyaDepartment of Radiology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Kohichi TakadaDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Akihiro MiyazakiDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Sapporo Medical University · JP

Funding

Japan Science for the Promotion of Science JSPSKAKENHI22K10197
6 · The paper itself

Abstract

backgroundAberrant Notch signaling pathway has been related with the tumorigenesis in head and neck region, involving oral cavity. Here, we report the correlation between mutations in the Notch signaling pathway and CD8

methodsThis retrospective study analyzed the results of immunohistochemical staining for PD-L1 and CD8

resultsFour of 10 patients were positive for PD-L1 and CD8

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsMouth NeoplasmsB7-H1 AntigenCD8-Positive T-LymphocytesHumansImmune Checkpoint InhibitorsRetrospective StudiesSquamous Cell Carcinoma of Head and NeckB7-H1 AntigenImmune Checkpoint InhibitorsCD8+ T cellimmunotherapynotch signaling geneoral squamous cell carcinoma

Identifiers

PMID38491819
PMCPMC10943361
OpenAlexW4392888769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.