ReviewImplementation science : IS2024
Generative AI in healthcare: an implementation science informed translational path on application, integration and governance.
Review in Implementation science : IS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 174 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
174 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Enhanced fracture detection on radiographs with AI assistance for clinicians: a systematic review and meta-analysis.Annals of medicine · 2026Pooled it
- Preferences for AI-Enabled Health Care Technologies: Systematic Review of Discrete Choice Experiments and Reporting Quality Assessment Using the DIRECT Checklist.Journal of medical Internet research · 2026Pooled it
- Artificial Intelligence Governance in Health Systems: Systematic Review of Frameworks and Integrative Model Proposal.Journal of medical Internet research · 2026Pooled it
- Evaluating Artificial Intelligence for Sepsis Prediction in Emergency Departments: A Systematic Review and Meta Analysis.Journal of medical systems · 2026Pooled it
- Effectiveness of pharmaceutical care interventions amid pharmacist role transformation in China: a meta-analysis.Frontiers in public health · 2026Pooled it
- The impact of generative AI on health professional education: A systematic review in the context of student learning.Medical education · 2025Pooled it
- Artificial intelligence in orthopaedic education, training and research: a systematic review.BMC medical education · 2025Pooled it
- Revolution or routine? Comparing AI and traditional imaging in thoracic surgery outcomes: a systematic review.Journal of medicine and life · 2025Pooled it
- The potentials and challenges of integrating generative artificial intelligence (AI) in dental and orthodontic education: a systematic review.BMC oral health · 2025Pooled it
- Impact of Artificial Intelligence-Based Technology on Nurse Management: A Systematic Review.Journal of nursing management · 2024Pooled it
- DeepSeek-assisted problem-based learning for glaucoma education in an undergraduate ophthalmology clerkship: a randomized educational pilot study.Scientific reports · 2026Trial
- Artificial intelligence and extracellular vesicles in oncology: towards tumor diagnosis, prediction, and therapy.Drug delivery · 2026Review
- Ethical and Regulatory Challenges of Generative Artificial Intelligence in Healthcare: A Chinese Perspective.Journal of clinical nursing · 2026Article
- Nurses' Engagement in Digital Health Clinical Trials Using Unobtrusive Monitoring Technologies: Constructivist Grounded Theory Study.Journal of medical Internet research · 2026Article
- Insights into the Complexities of Pharmacotherapy Parameters in Artificial Intelligence Models for Drug Selection, Precision Personalised Medicine and Optimal Therapeutic Outcomes.Pharmaceutics · 2026Review
- Building health-literate artificial intelligence.Nature human behaviour · 2026Review
- Consensus framework for the validation of generative AI: call for collaborators on the Validation Accords.Nature medicine · 2026Article
- Consumer and Patient Health Information Seeking With Generative AI Tools: Scoping Review of Facilitators and Barriers.Journal of medical Internet research · 2026Article
- Guidance for laboratory implementation, governance and continuous assurance of artificial intelligence in histopathology.Virchows Archiv : an international journal of pathology · 2026Review
- Integrating artificial intelligence into venous thromboembolism care: Predictive models, implementation challenges, and future directions.Journal of vascular surgery. Venous and lymphatic disorders · 2026Article
114 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArtificial intelligence (AI), particularly generative AI, has emerged as a transformative tool in healthcare, with the potential to revolutionize clinical decision-making and improve health outcomes. Generative AI, capable of generating new data such as text and images, holds promise in enhancing patient care, revolutionizing disease diagnosis and expanding treatment options. However, the utility and impact of generative AI in healthcare remain poorly understood, with concerns around ethical and medico-legal implications, integration into healthcare service delivery and workforce utilisation. Also, there is not a clear pathway to implement and integrate generative AI in healthcare delivery.
methodsThis article aims to provide a comprehensive overview of the use of generative AI in healthcare, focusing on the utility of the technology in healthcare and its translational application highlighting the need for careful planning, execution and management of expectations in adopting generative AI in clinical medicine. Key considerations include factors such as data privacy, security and the irreplaceable role of clinicians' expertise. Frameworks like the technology acceptance model (TAM) and the Non-Adoption, Abandonment, Scale-up, Spread and Sustainability (NASSS) model are considered to promote responsible integration. These frameworks allow anticipating and proactively addressing barriers to adoption, facilitating stakeholder participation and responsibly transitioning care systems to harness generative AI's potential.
resultsGenerative AI has the potential to transform healthcare through automated systems, enhanced clinical decision-making and democratization of expertise with diagnostic support tools providing timely, personalized suggestions. Generative AI applications across billing, diagnosis, treatment and research can also make healthcare delivery more efficient, equitable and effective. However, integration of generative AI necessitates meticulous change management and risk mitigation strategies. Technological capabilities alone cannot shift complex care ecosystems overnight; rather, structured adoption programs grounded in implementation science are imperative.
conclusionsIt is strongly argued in this article that generative AI can usher in tremendous healthcare progress, if introduced responsibly. Strategic adoption based on implementation science, incremental deployment and balanced messaging around opportunities versus limitations helps promote safe, ethical generative AI integration. Extensive real-world piloting and iteration aligned to clinical priorities should drive development. With conscientious governance centred on human wellbeing over technological novelty, generative AI can enhance accessibility, affordability and quality of care. As these models continue advancing rapidly, ongoing reassessment and transparent communication around their strengths and weaknesses remain vital to restoring trust, realizing positive potential and, most importantly, improving patient outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.