ArticleHarm reduction journal2024
A confirmed case of xylazine-induced skin ulcers in a person who injects drugs in Miami, Florida, USA.
Article in Harm reduction journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 25 citations in OpenAlex.
- Healthcare provider approaches to managing the health harms of xylazine: A qualitative study.Journal of substance use and addiction treatment · 2026Article
- Article
- Surgical Challenges and Harm-reduction Strategies in Xylazine-associated Wounds: A Systematic Review.Plastic and reconstructive surgery. Global open · 2026Article
- Drug-Checking with Molecularly Imprinted Polymers: Addressing Xylazine-Contaminated Fentanyl.ACS sensors · 2025Article
- Bacterial and fungal infections in persons who inject drugs.Clinical microbiology reviews · 2025Review
- HEAL-X: A Novel Classification System for Xylazine Associated Wounds.International wound journal · 2025Article
- Destructive Xylazine Wounds: A New Entity Faced by Thoracic Surgeons.Annals of thoracic surgery short reports · 2025Article
- Adsorptive Cathodic Stripping Analysis of Xylazine Within Fouling-Resistant and Nanomaterial-Enhanced Modified Electrode Sensors.Sensors (Basel, Switzerland) · 2025Article
- Xylazine Induced Skin Necrosis.Journal of general internal medicine · 2025Article
- Managing xylazine-involved overdoses in a community harm reduction setting: lessons from Tijuana, Mexico.Harm reduction journal · 2025Article
- Letter Regarding "Xylazine-Associated Wounds of the Upper Extremity: Evaluation and Algorithmic Surgical Strategy".Journal of hand surgery global online · 2024Article
- Xylazine abuse, the growing risk: A review of its effects, upsurge use and associated fatalities in the USA and Puerto Rico.Journal of forensic and legal medicine · 2024Review
- An Amperometric Sensor with Anti-Fouling Properties for Indicating Xylazine Adulterant in Beverages.Micromachines · 2024Article
- Fouling-Resistant Voltammetric Xylazine Sensors for Detection of the Street Drug "Tranq".Toxics · 2024Article
- Syringe services program staff and participant perspectives on changing drug consumption behaviors in response to xylazine adulteration.Harm reduction journal · 2024Article
- Protective or potentially harmful? Altering drug consumption behaviors in response to xylazine adulteration.Research square · 2024Article
- Fentanyl and xylazine crisis: Crafting coherent strategies for opioid overdose prevention.World journal of psychiatry · 2024Article
- Treatment of Xylazine-Associated Injection Skin Injuries.Case reports in dermatological medicine · 2024Article
- Development and Validation of an Image-Based Deep Learning Tool for Identification of Xylazine-Associated Wounds.Journal of addiction medicineArticle
- A composite vignette: xylazine, infectious complications and the importance of community-based drug checking services.Therapeutic advances in infectious diseaseArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundXylazine is an alpha-2 adrenergic receptor agonist that has emerged as a contaminant in the illicit drug supply of fentanyl. Xylazine use may be suspected in naloxone-resistant overdoses and atypical, chronic wounds in people who use drugs (PWUD). This case is unique because it is the first case to our knowledge describing wound care for a xylazine-induced wound with a confirmatory xylazine test strip (XTS) in the setting of a syringe services program (SSP) and in the state of Florida. CASE PRESENTATION: A 43-year-old woman with a past medical history of severe opioid use disorder and stimulant use disorder presented to a student-run clinic at a Miami SSP for wound care. She had multiple ulcerations diffusely over her bilateral forearms with surrounding erythema and warmth. Seven weeks later, she presented to clinic again for wound care because her wounds had progressed. At this visit, a XTS was used to confirm the presence of xylazine in her urine. Wound care management and harm reduction strategies employed at both visits were informed by best clinical judgement due to lack of formal guidelines at the time. Wound outcomes are unknown as the patient has not returned to clinic.
conclusionsMany PWUD at highest risk for acute and chronic health consequences of xylazine-adulterated fentanyl do not have access to healthcare outside of low barrier clinics and SSPs due to lack of insurance or mistrust of the traditional healthcare system due to stigma. There is an urgent need for access to XTS for PWUD and clinical practice guidelines for the treatment of xylazine-related wounds in outpatient clinics.
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