ArticleBMC public health2024
The impact of caregiver burden on quality of life in family caregivers of patients with advanced cancer: a moderated mediation analysis of the role of psychological distress and family resilience.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Caregiver burden, anxiety, and quality-of-life among informal caregivers of patient with head and neck cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Interventions for reducing caregiver burden in chronic dyspnea: a meta-analysis.Frontiers in public health · 2025Pooled it
- Nonpharmacologic interventions for managing distress, anxiety, and depression for patients with cancer and their family caregivers: A systematic review and meta-analysis.CA: a cancer journal for cliniciansPooled it
- Quality of life and appraisal factors of patients with advanced cancer and their family caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Trial
- Modifiable pre-operative physiological predictors of length of stay following shoulder arthroplasty: a systematic review.JSES reviews, reports, and techniques · 2026Review
- Comparison of parental caregivers and associated factors with caregiver burden in rare paediatric diseases.Orphanet journal of rare diseases · 2026Article
- Association Between Health-Related Quality of Life In Patients with Colorectal Cancer and Their Informal Caregivers.Advances in therapy · 2026Article
- Article
- Article
- Caregiver contribution to patient self‑care and quality of life among informal carers of adult patients with inflammatory bowel disease: a cross‑sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Participants' Evolving Experiences, Hope, and Coping While Enrolled in a Community-Based Bereavement Support Program: A Pre-Post Mixed-Methods Pilot Study.Current oncology (Toronto, Ont.) · 2026Article
- Effect of a nurse-led dyadic symptom management intervention on postoperative esophageal cancer patients and their family caregivers: A quasi-experimental trial with a qualitative process evaluation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Suicidal ideation in family caregivers of patients with dementia, cancer, stroke, and ischemic heart disease.Annals of general psychiatry · 2026Article
- Nurse-led remote symptom management for chemotherapy toxicity and quality of life in lymphoma: a quasi-experimental study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Investigating the association between self-compassion and caregiving burden in caregivers of adults with cancer: a cross-sectional study.BMC nursing · 2026Article
- Psychometric evaluation of the Chinese CancerSupportSourceHealth and quality of life outcomes · 2026Article
- Quality of life and burden in family caregivers of advanced cancer patients in the Grand Duchy of Luxembourg: results from a single-centre study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Evaluating the Applicability of the Self-Assessment Tool for Family Caregivers (SSA-PA) in Care Counseling According to Section 45 of the German Social Code (SGB XI): A Mixed-Methods Study.Healthcare (Basel, Switzerland) · 2026Article
- Dyadic Risk and Protective Factors of Caregiver Burden Among Partners of Patients With Advanced Cancer: A Network Approach.Psycho-oncology · 2026Article
- Grief and Psychopathology in Bereaved Caregivers of Palliative Care Patients: The Mediating and Moderating Roles of Distress, Burden and Social Support.Journal of advanced nursing · 2026Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe caregiver burden frequently experienced by family members tending to advanced cancer patients significantly impacts their psychological well-being and quality of life (QoL). Although family resilience might function as a mitigating factor in this relationship, its specific role remains to be elucidated. This study aims to probe the mediating effect of psychological distress on the relationship between caregiver burden and QoL, as well as the moderating effect of family resilience.
methodsA cross-sectional study was conducted between June 2020 and March 2021 in five tertiary hospitals in China. Data were collected on caregiver burden, family resilience, psychological distress (including anxiety and depression), and QoL. Moderated mediation analysis was performed.
resultsData analysis included 290 caregivers. It confirmed the mediating role of psychological distress in the caregiver burden-QoL relationship (P < 0.001). Both overall family resilience and the specific dimension of family communication and problem-solving (FCPS) demonstrated significant moderating effects on the "psychological distress/anxiety-QoL" paths (P < 0.05). The utilization of social and economic resources (USER) significantly moderated the association between depression and QoL (P < 0.05).
conclusionsThe study corroborates psychological distress's mediation between caregiver burden and QoL and family resilience's moderation between psychological distress and QoL. It underscores the need for minimizing psychological distress and bolstering family resilience among caregivers of advanced cancer patients. Accordingly, interventions should be tailored, inclusive of psychological assistance and promotion of family resilience, particularly focusing on FCPS and USER, to augment the caregivers' well-being and QoL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.