Evidence map›Paper›PMID 38491201›Full record

ArticleLasers in medical science2024

Synergistic effect of mesoporous silica nanocarrier-assisted photodynamic therapy and anticancer agent activity on lung cancer cells.

Burcu Güleryüz, Ayşe Işık, Murat Gülsoy

Open access · hybridAbstract read
In one paragraph

Article in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Burcu GüleryüzInstitute of Biomedical Engineering, Bogazici University, Uskudar, Istanbul, 34684, Turkey. burcu.guleryuz@boun.edu.tr.ORCID http://orcid.org/0000-0003-0762-5567
Ayşe IşıkInstitute of Biomedical Engineering, Bogazici University, Uskudar, Istanbul, 34684, Turkey. ayse.isik@boun.edu.tr.
Murat GülsoyInstitute of Biomedical Engineering, Bogazici University, Uskudar, Istanbul, 34684, Turkey.
Boğaziçi University · TRÜsküdar University · TR

Funding

Boğaziçi University Research Fund 22XP1
6 · The paper itself

Abstract

Investigating combined treatment methodologies is crucial for addressing the complex nature of cancer. As an emerging strategy, nano-biotechnology encourages the design of unique nanocarriers possessing simultaneous therapeutic application properties. This study aims to explore the combined effects of photodynamic and anticancer treatments using a multifunctional nanocarrier system co-administering the photosensitizer IR780 and the anticancer agent curcumin (Cur) on lung cancer cells. Nanocarriers were prepared by encapsulation IR780 and Cur inside polyethylene glycol-capped mesoporous silica nanoparticles (Cur&IR780@MSN). Various concentrations of nanocarriers were evaluated on A549 cells following 5 min NIR laser light (continuous wave, 785 nm, 500 mW/cm

Indexed as

Antineoplastic AgentsCurcuminLung NeoplasmsNanoparticlesPhotochemotherapyDrug CarriersHumansSilicon DioxideAntineoplastic AgentsCurcuminDrug CarriersSilicon DioxideAnticancer TherapyCombination TherapyLung CancerNanomedicinePhotodynamic Therapy

Identifiers

PMID38491201
PMCPMC10942901
OpenAlexW4394740062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.