Evidence map›Paper›PMID 38491141›Full record

Observational studyPediatric research2024

Aerobic physical capacity and health-related quality of life in children with sickle cell disease.

Corentin Laurent-Lacroix, Marie Vincenti, Stefan Matecki, Perrine Mahé, Lionel Moulis, Gregoire De La Villeon, Sophie Guillaumont, Anne Requirand, Johan Moreau, Muriel Lalande and 3 more

2 registry-linked trialsAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05995743 completednot on this map

Aerobic Physical Fitness and Health-related Quality of Life in Children With Sickle Cell Disease.

TypeobservationalSponsorUniversity Hospital, MontpellierRan2021 to 2022Enrolled72ConditionsSickle Cell, Children
NCT07728435 completednot on this mapstarted 2025, after this paper: background citation

Cardiopulmonary Fitness and Health-Related Quality of Life in Children and Adolescents With Type 1 Diabetes: The Prospective Multicenter Controlled FIT-T1D Study

TypeobservationalSponsorInstitut Saint PierreRan2025 to 2026Enrolled214ConditionsDiabete Type 1
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Early and Stage-Dependent Cardiopulmonary Fitness Impairment in Pediatric CKD.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Corentin Laurent-LacroixDepartment of Pediatric and Congenital Cardiology, M3C Regional Reference CHD Centre, Montpellier University Hospital, 371 Avenue du Doyen Giraud, 34295, Montpellier, France.
Marie VincentiDepartment of Pediatric and Congenital Cardiology, M3C Regional Reference CHD Centre, Montpellier University Hospital, 371 Avenue du Doyen Giraud, 34295, Montpellier, France.
Stefan MateckiPhyMedExp, CNRS, INSERM, University of Montpellier, 371 Avenue du Doyen Giraud, 34295, Montpellier, France.
Perrine MahéPediatric Department, Montpellier University Hospital, 371 Avenue du Doyen Giraud, 34295, Montpellier, France.
Lionel MoulisClinical Research and Epidemiology Unit, Montpellier University Hospital, 34000, Montpellier, France.
Gregoire De La VilleonDepartment of Pediatric and Congenital Cardiology, M3C Regional Reference CHD Centre, Montpellier University Hospital, 371 Avenue du Doyen Giraud, 34295, Montpellier, France.
Sophie GuillaumontDepartment of Pediatric and Congenital Cardiology, M3C Regional Reference CHD Centre, Montpellier University Hospital, 371 Avenue du Doyen Giraud, 34295, Montpellier, France.
Anne RequirandPediatric Functional Exploration Laboratory, Physiology Department, Montpellier University Hospital, 371 Avenue du Doyen Giraud, 34295, Montpellier, France.
Johan MoreauPediatric Functional Exploration Laboratory, Physiology Department, Montpellier University Hospital, 371 Avenue du Doyen Giraud, 34295, Montpellier, France.
Muriel LalandePediatric Department, Montpellier University Hospital, 371 Avenue du Doyen Giraud, 34295, Montpellier, France.
Marie-Christine PicotClinical Research and Epidemiology Unit, Montpellier University Hospital, 34000, Montpellier, France.
Pascal AmedroDepartment of Pediatric and Congenital Cardiology, M3C National Reference Centre, Bordeaux University Hospital, 1 Avenue Magellan, 33604, Pessac, France.
Arthur GavottoPhyMedExp, CNRS, INSERM, University of Montpellier, 371 Avenue du Doyen Giraud, 34295, Montpellier, France. a-gavotto@chu-montpellier.fr.ORCID 0000-0001-6485-7634
Université de Montpellier · FRCentre National de la Recherche Scientifique · FRInserm · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAerobic fitness is a predictor of cardiovascular health which correlates with health-related quality of life in the general population. The aim is to evaluate the aerobic capacity by cardiopulmonary exercise test (CPET) in children with sickle cell disease in comparison with healthy matched controls.

methodsControlled cross-sectional study.

resultsA total of 72 children (24 with sickle cell disease and 48 healthy controls), aged 6-17 years old were enrolled. Children with sickle cell disease had a poor aerobic capacity, with median VO

conclusionAerobic capacity is poor in children with sickle cell disease. VO CLINICAL TRIALS: NCT05995743. IMPACT: Aerobic fitness is a predictor of cardiovascular health which correlates with health-related quality of life in the general population. Aerobic capacity (VO

Indexed as

Anemia, Sickle CellExercise TestExercise ToleranceQuality of LifeAdolescentCase-Control StudiesChildCross-Sectional StudiesExerciseFemaleHumansMaleOxygen ConsumptionPhysical Fitness

Identifiers

PMID38491141
OpenAlexW4392864998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.