Evidence map›Paper›PMID 38490949›Full record

ReviewGenesis (New York, N.Y. : 2000)2024

Deficits in olfactory system neurogenesis in neurodevelopmental disorders.

Sean C Sweat, Claire E J Cheetham

Open access · greenAbstract readReview
In one paragraph

Review in Genesis (New York, N.Y. : 2000), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. International journal of molecular sciences · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sean C SweatDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-7598-3166
Claire E J CheethamDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-4038-1501
University of Pittsburgh · US

Funding

Medical Scientist Training ProgramT32GM144300 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RICHARD A STEINMAN, Russell S Schwartz · 2022 to 2026
$7.9M
Functional Integration of Newborn Olfactory Sensory Neurons in the Healthy and Regenerating Olfactory SystemR01DC018516 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHEETHAM, CLAIRE ELIZABETH JANE · 2021 to 2025
$1.8M
NIDCD NIH HHS R01 DC018516NIDCD NIH HHS R01DC018516NIGMS NIH HHS T32 GM144300
6 · The paper itself

Abstract

The role of neurogenesis in neurodevelopmental disorders (NDDs) merits much attention. The complex process by which stem cells produce daughter cells that in turn differentiate into neurons, migrate various distances, and form synaptic connections that are then refined by neuronal activity or experience is integral to the development of the nervous system. Given the continued postnatal neurogenesis that occurs in the mammalian olfactory system, it provides an ideal model for understanding how disruptions in distinct stages of neurogenesis contribute to the pathophysiology of various NDDs. This review summarizes and discusses what is currently known about the disruption of neurogenesis within the olfactory system as it pertains to attention-deficit/hyperactivity disorder, autism spectrum disorder, Down syndrome, Fragile X syndrome, and Rett syndrome. Studies included in this review used either human subjects, mouse models, or Drosophila models, and lay a compelling foundation for continued investigation of NDDs by utilizing the olfactory system.

Indexed as

Autism Spectrum DisorderFragile X SyndromeNeurodevelopmental DisordersAnimalsHumansMammalsMiceNeurogenesisNeuronsneurodevelopmental disordersneurogenesisolfactory system

Identifiers

PMID38490949
PMCPMC10990073
OpenAlexW4392882815

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.