Evidence map›Paper›PMID 38490912›Full record

ArticleSocial science & medicine (1982)2024

Clinical and sociodemographic characteristics as predictors for quality of life in transmasculine and transfeminine individuals receiving gender-affirming hormone therapy.

Saloni U Lad, Jacob Sinopoli, Brian Khong, Britt Conroy, Adam T Perzynski, Juan P Del Rincon

Open access · greenAbstract read
In one paragraph

Article in Social science & medicine (1982), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Saloni U LadCleveland Clinic Lerner College of Medicine, 9501 Euclid Ave., Cleveland, OH, 44195, USA. Electronic address: sul2@case.edu.
Jacob SinopoliThe Chester Summer Scholars Program, MetroHealth Medical System, 2500 MetroHealth Drive, Cleveland, OH, 44109, USA; Case Western Reserve University, Cleveland, OH, USA. Electronic address: jts156@case.edu.
Brian KhongDepartment of Medicine, MetroHealth System, 2500 MetroHealth Drive, Cleveland, OH, 44109, USA. Electronic address: brian.khong@gmail.com.
Britt ConroyCase Western Reserve University, Cleveland, OH, USA; Department of Urology and Family Medicine & Community Health, University Hospitals Cleveland Medical Center, 11100 Euclid Ave., Cleveland, OH, 44106, USA. Electronic address: britt.conroy2@uhhospitals.org.
Adam T PerzynskiCenter for Healthcare Research and Policy, Case Western Reserve University at MetroHealth, 10900 Euclid Ave., Cleveland, OH, 44106, USA. Electronic address: adam.perzynski@case.edu.
Juan P Del RinconCase Western Reserve University, Cleveland, OH, USA; Department of Medicine, MetroHealth System, Cleveland, OH, USA; Endocrinology and Metabolism Institute, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH, 44195, USA. Electronic address: jxd232@case.edu.
MetroHealth · USCleveland Clinic Lerner College of Medicine · USMetroHealth Medical Center · USUniversity Hospitals of Cleveland · US

Funding

Modeling and Forecasting Atherosclerotic Risk: A Complex Systems ApproachR01AG055480 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI DALTON, JARROD, PERZYNSKI, ADAM THOMAS · 2017 to 2020
$2.8M
Effect of Bariatric Surgery on Mechanisms of Type 2 Diabetes: The B2D TrialR01DK089547 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI KASHYAP, SANGEETA R, KIRWAN, JOHN P. · 2010 to 2013
$1.9M
NIA NIH HHS R01 AG055480NIDDK NIH HHS R01 DK089547
6 · The paper itself

Abstract

Healthcare systems and providers have increasingly acknowledged the role and impact of social determinants in overall health. However, gender-diverse individuals face persistent health disparities due to their identities. There is limited research on the impact of clinical and sociodemographic characteristics on mood and quality of life (QoL) for transgender (TG) individuals. Our study aims to understand and better elucidate social and clinical characteristics of transmasculine (TM) and transfeminine (TF) individuals and their impact on quality of life and depressive symptoms. In this cross-sectional study, 298 TF and TM individuals on gender-affirming hormone therapy (GAHT) were surveyed about their demographic characteristics (age, gender identity, body mass index (BMI), and education), social needs, mood, and quality of life. Multivariable regression modelling was performed to assess the effect of each variable listed above on three domains of QoL (psychological, environmental, and physical) as well as depressive symptoms. We find that QoL scores are similar between TM and TF individuals, with scores in the psychological domain particularly low in both cohorts. TM individuals report higher rates of stress and restroom avoidance than TF individuals. In particular, psychological well-being (measured by the psychological domain of QoL and depressive symptoms) is significantly associated with increased BMI, financial instability, and stress in TM individuals while for TF individuals, psychological well-being is associated with stress and social integration. These data suggest that social circumstances are key drivers of QoL and psychological well-being among gender-diverse individuals receiving GAHT with specific differences between TF and TM individuals. This information may be utilized by healthcare providers and policymakers to address and improve clinical care and social policies to improve health equity for gender-diverse individuals.

Indexed as

Transgender PersonsTranssexualismCross-Sectional StudiesFemaleGender IdentityHormonesHumansMaleQuality of LifeHormonesGender-affirming hormone therapyQuality of lifeSocial determinants of healthTransgender medicine

Identifiers

PMID38490912
PMCPMC11635758
OpenAlexW4392575487

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.