ArticlePhysiological reports2024
Skeletal muscle adaptations to high-intensity, low-volume concurrent resistance and interval training in recreationally active men and women.
Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Sex differences in human skeletal muscle fiber types and the influence of age, physical activity, and muscle group: A systematic review and meta-analysis.Physiological reports · 2025Pooled it
- Effects of strength training on neuromuscular adaptations in the development of maximal strength: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Effect of resistance training on body composition and physical function in older females with sarcopenic obesity-a systematic review and meta-analysis of randomized controlled trials.Frontiers in aging neuroscience · 2025Pooled it
- Pooled it
- Trial
- Concurrent HIIT and Resistance Training for Musculoskeletal Function: A Systematic Review of Neuromuscular, Morphological, and Performance Adaptations.Life (Basel, Switzerland) · 2026Review
- Beyond hypertrophy: a network physiology perspective on the cardio-neuromuscular trade-off in elite soccer.Frontiers in network physiology · 2026Article
- The role of exercise-mediated mitochondrial quality control remodeling in aging.Frontiers in cell and developmental biology · 2026Review
- Effects of Off-Season Heavy-Load Resistance Training on Lower Limb Mechanical Muscle Function and Physical Performance in Elite Female Team Handball Players.Journal of functional morphology and kinesiology · 2024Article
- Circulating extracellular vesicle characteristics differ between men and women following 12 weeks of concurrent exercise training.Physiological reports · 2024Article
- Skeletal muscle adaptations to high-intensity, low-volume concurrent resistance and interval training in recreationally active men and women.Physiological reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 2 institutions in 2 countries.
Funding
Abstract
This study compared the structural and cellular skeletal muscle factors underpinning adaptations in maximal strength, power, aerobic capacity, and lean body mass to a 12-week concurrent resistance and interval training program in men and women. Recreationally active women and men completed three training sessions per week consisting of high-intensity, low-volume resistance training followed by interval training performed using a variety upper and lower body exercises representative of military occupational tasks. Pre- and post-training vastus lateralis muscle biopsies were analyzed for changes in muscle fiber type, cross-sectional area, capillarization, and mitochondrial biogenesis marker content. Changes in maximal strength, aerobic capacity, and lean body mass (LBM) were also assessed. Training elicited hypertrophy of type I (12.9%; p = 0.016) and type IIa (12.7%; p = 0.007) muscle fibers in men only. In both sexes, training decreased type IIx fiber expression (1.9%; p = 0.046) and increased total PGC-1α (29.7%, p < 0.001) and citrate synthase (11.0%; p < 0.014) content, but had no effect on COX IV content or muscle capillarization. In both sexes, training increased maximal strength and LBM but not aerobic capacity. The concurrent training program was effective at increasing strength and LBM but not at improving aerobic capacity or skeletal muscle adaptations underpinning aerobic performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.