Evidence map›Paper›PMID 38490690›Full record

ArticleBMJ mental health2024

Psychological burden associated with incident persistent symptoms and their evolution during the COVID-19 pandemic: a prospective population-based study.

Baptiste Pignon, Joane Matta, Emmanuel Wiernik, Anne Toussaint, Bernd Loewe, Olivier Robineau, Fabrice Carrat, Gianluca Severi, Mathilde Touvier, Clement Gouraud and 8 more

Open access · diamondAbstract read
In one paragraph

Article in BMJ mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 3 countries.

Baptiste PignonPopulation-based Cohorts Unit, Paris Saclay University, Paris, France baptistepignon@yahoo.fr.ORCID http://orcid.org/0000-0003-0526-3136
Joane MattaPopulation-based Cohorts Unit, Paris Saclay University, Paris, France.
Emmanuel WiernikPopulation-based Cohorts Unit, Paris Saclay University, Paris, France.
Anne ToussaintKlinik und Poliklinik für Psychosomatische Medizin und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Bernd LoeweKlinik und Poliklinik für Psychosomatische Medizin und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Olivier RobineauSorbonne Université, Inserm, Institut Pierre-Louis d'Epidémiologie et de Santé Publique, Paris, France.
Fabrice CarratSorbonne Université, Inserm, Institut Pierre-Louis d'Epidémiologie et de Santé Publique, Paris, France.
Gianluca SeveriUniversité Paris-Saclay, UVSQ, INSERM, CESP U1018, Gustave Roussy, Villejuif, France.
Mathilde TouvierSorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Nutritional Epidemiology Research Team (EREN), Centre of Research in Epidemiology and Statistics (CRESS) - Université Paris Cité (CRESS), Bobigny, France.
Clement GouraudService de Psychiatrie de l'adulte, AP-HP, Hôpital Hôtel-Dieu, Paris, France.
Charles Ouazana VedrinesService de Psychiatrie de l'adulte, AP-HP, Hôpital Hôtel-Dieu, Paris, France.
Victor PitronUniversité Paris Cité, VIFASOM (Vigilance Fatigue Sommeil et Santé Publique), Paris, France.
Brigitte RanqueUniversité Paris Cité, Service de Médecine interne, AP-HP, Hôpital européen Georges-Pompidou, Paris, France.
Nicolas HoertelUniversité Paris Cité, INSERM U1266, Institut de Psychiatrie et Neuroscience de Paris, Paris, France.
Sofiane KabPopulation-based Cohorts Unit, Paris Saclay University, Paris, France.
Marcel GoldbergPopulation-based Cohorts Unit, Paris Saclay University, Paris, France.
Marie ZinsPopulation-based Cohorts Unit, Paris Saclay University, Paris, France.
Cédric LemogneService de Psychiatrie de l'adulte, AP-HP, Hôpital Hôtel-Dieu, Paris, France.
Inserm · FRUniversité Paris-Saclay · FRUniversität Hamburg · DEUniversité Paris Cité · FRAssistance Publique – Hôpitaux de Paris · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdentifying factors that predict the course of persistent symptoms that occurred during the COVID-19 pandemic is a public health issue. Modifiable factors could be targeted in therapeutic interventions.

objectiveThis prospective study based on the population-based CONSTANCES cohort examined whether the psychological burden associated with incident persistent symptoms (ie, that first occurred from March 2020) would predict having ≥1 persistent symptom 6-10 months later.

methodsA total of 8424 participants (mean age=54.6 years (SD=12.6), 57.2% women) having ≥1 incident persistent symptom at baseline (ie, between December 2020 and February 2021) were included. The psychological burden associated with these persistent symptoms was assessed with the Somatic Symptom Disorder-B Criteria Scale (SSD-12). The outcome was having ≥1 persistent symptom at follow-up. Adjusted binary logistic regression models examined the association between the SSD-12 score and the outcome.

findingsAt follow-up, 1124 participants (13.3%) still had ≥1 persistent symptom. The SSD-12 score at baseline was associated with persistent symptoms at follow-up in both participants with (OR (95% CI) for one IQR increase: 1.42 (1.09 to 1.84)) and without SARS-CoV-2 infection prior to baseline (1.39 (1.25 to 1.55)). Female gender, older age, poorer self-rated health and infection prior to baseline were also associated with persistent symptoms at follow-up.

conclusionsThe psychological burden associated with persistent symptoms at baseline predicted the presence of ≥1 persistent symptom at follow-up regardless of infection prior to baseline. CLINICAL IMPLICATIONS: Intervention studies should test whether reducing the psychological burden associated with persistent symptoms could improve the course of these symptoms.

Indexed as

COVID-19Mental DisordersFemaleHumansMaleMiddle AgedPandemicsProspective StudiesSARS-CoV-2COVID-19

Identifiers

PMID38490690
PMCPMC11021747
OpenAlexW4392869903

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.