Evidence map›Paper›PMID 38490221›Full record

ArticleThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2025

Can MRI Replace Nasopharyngoscopy in the Evaluation of Velopharyngeal Insufficiency?

Jessica L Williams, Jamie L Perry, Taylor D Snodgrass, Davinder J Singh, M'hamed Temkit, Thomas J Sitzman

Abstract read
In one paragraph

Article in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
7.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. What is the Patient Compliance Rate for Nasopharyngoscopy as Documented in Clinical Reports?The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  2. Article
  3. An Exploratory Investigation into the Influence of Nasopharyngoscopy Findings on VPI Surgery Selection.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  4. Management of Persistent Hypernasality After Pharyngeal Flap by Revision Palatoplasty With Use of MRI to Aid Surgical Decision Making.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  5. How Do Nasopharyngoscopy Ratings of Sustained Speech Differ From Connected Speech?The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Observational
  6. Article
  7. Factors That Limit Evaluation of Velopharyngeal Closure During Nasopharyngoscopy.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2025
    Observational
  8. Levator Veli Palatini Muscle Ratio Is a Clinically Significant Anatomic Predictor for Velopharyngeal Surgical Need.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2025
    Observational
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jessica L WilliamsPhoenix Children's Center for Cleft and Craniofacial, Phoenix Children's Hospital, Phoenix, AZ, USA.ORCID 0000-0002-2882-7275
Jamie L PerryDepartment of Communication Sciences and Disorders, East Carolina University, Greenville, NC, USA.ORCID 0000-0001-7866-9159
Taylor D SnodgrassDepartment of Communication Sciences and Disorders, East Carolina University, Greenville, NC, USA.ORCID 0000-0001-8315-6016
Davinder J SinghPhoenix Children's Center for Cleft and Craniofacial, Phoenix Children's Hospital, Phoenix, AZ, USA.
M'hamed TemkitDepartment of Clinical Research, Phoenix Children's Hospital, Phoenix, AZ, USA.
Thomas J SitzmanPhoenix Children's Center for Cleft and Craniofacial, Phoenix Children's Hospital, Phoenix, AZ, USA.ORCID 0000-0002-2173-923X
East Carolina University · USPhoenix Children's Hospital · USUniversity of Arizona · US

Funding

Velopharyngeal insufficiency following cleft palate repair: a comparative effectiveness study of existing surgical procedures and identification of criteria to guide a personalized treatment approachU01DE029750 · NIDCR · PHOENIX CHILDREN'S HOSPITAL · PI SITZMAN, THOMAS JAMES · 2020 to 2024
$4.2M
Understanding and Reducing Variation in Outcomes of Cleft Lip and Palate SurgeryK23DE025023 · NIDCR · PHOENIX CHILDREN'S HOSPITAL · PI SITZMAN, THOMAS JAMES · 2016 to 2020
$598k
NIDCR NIH HHS K23 DE025023NIDCR NIH HHS U01 DE029750
6 · The paper itself

Abstract

ObjectiveTo investigate whether flexible nasopharyngoscopy, when performed in addition to magnetic resonance imaging (MRI), influences the type of surgery selected or success of surgery in patients with velopharyngeal insufficiency (VPI).DesignCohort study.SettingA metropolitan children's hospital.PatientsPatients with non-syndromic, repaired cleft palate presenting for management of VPI.InterventionsMRI and nasopharyngoscopy or MRI alone for preoperative imaging of the velopharyngeal mechanism.Main Outcome Measures(1) Surgical selection and (2) resolution of hypernasality. All speech, MRI, and nasopharyngoscopy measurements were performed by raters blinded to patients' medical and surgical history.ResultsOf the 25 patients referred for nasopharyngoscopy, 76% completed the exam. Of the 41 patients referred for MRI, the scan was successfully completed by 98% of patients. Completion of nasopharyngoscopy was significantly (p=0.01) lower than MRI. Surgical selection did not significantly differ (p=0.73) between the group receiving MRI and nasopharyngoscopy and the group receiving MRI alone, nor was there a significant difference between these groups in the proportion of patients achieving resolution of hypernasality postoperatively (p=0.63). Percent total velopharyngeal closure assessments on nasopharyngoscopy and MRI were strongly correlated (r=0.73).ConclusionsIn patients receiving MRI as part of their preoperative VPI evaluation, the addition of nasopharyngoscopy did not result in a difference in surgical selection or resolution of hypernasality. Routine inclusion of nasopharyngoscopy may not be necessary for the evaluation of velopharyngeal anatomy when MRI is available.

Indexed as

EndoscopyMagnetic Resonance ImagingVelopharyngeal InsufficiencyAdolescentChildChild, PreschoolCleft PalateFemaleHumansInfantMaleTreatment Outcomecleft palatehypernasalityimagingMRInasoendoscopynonsyndromic cleftingresonance

Identifiers

PMID38490221
PMCPMC11401959
OpenAlexW4392855268

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.