Evidence map›Paper›PMID 38489917›Full record

ArticleMaturitas2024

Laparoscopically confirmed endometriosis and anti-Müllerian hormone levels: Findings from the Nurses' Health Study II.

Leslie V Farland, Michelle Valenti, William J Degnan, Elizabeth R Bertone-Johnson, Holly R Harris, Amy D DiVasta, Kathryn M Rexrode, A Heather Eliassen, Stacey A Missmer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Maturitas, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Leslie V FarlandDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, Department of Obstetrics and Gynecology, College of Medicine -Tucson, University of Arizona, 1295 N. Martin Ave, Tucson, AZ 85724, USA. Electronic address: lfarland@email.arizona.ed.
Michelle ValentiDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, 1295 N. Martin Ave, Tucson, AZ 85724, USA. Electronic address: michellevalenti@arizona.edu.
William J DegnanDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, 1295 N. Martin Ave, Tucson, AZ 85724, USA. Electronic address: wjd3@arizona.edu.
Elizabeth R Bertone-JohnsonDepartment of Biostatistics and Epidemiology, Department of Health Promotion and Policy, University of Massachusetts Amherst, 301 Arnold House, 715 North Pleasant Street, Amherst, MA 01003, USA. Electronic address: ebertone@schoolph.umass.edu.
Holly R HarrisProgram in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Center, 1100 Fairview Ave North, Seattle, WA, 98109, USA. Electronic address: hharris@fredhutch.org.
Amy D DiVastaDivision of Adolescent and Young Adult Medicine, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA, 02115, USA. Electronic address: amy.divasta@childrens.harvard.edu.
Kathryn M RexrodeDivision of Women's Health, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA. Electronic address: krexrode@bwh.harvard.edu.
A Heather EliassenChanning Division of Network Medicine, Brigham and Women's Hospital, Department of Epidemiology, Department of Nutrition, Harvard T.H. Chan School of Public Health, 181 Longwood Ave, Boston, MA, 02115, USA. Electronic address: nhahe@channing.harvard.edu.
Stacey A MissmerDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Department of Obstetrics, Gynecology, and Reproductive Biology, College of Human Medicine, Michigan State University, 15 Michigan St. NE, Grand Rapids, MI, 49503, USA. Electronic address: stacey.missmer@hc.msu.edu.
University of Arizona · USBrigham and Women's Hospital · USBoston Children's Hospital · USFred Hutch Cancer Center · USMichigan State University · USUniversity of Massachusetts Amherst · US

Funding

Life Course Cancer Epidemiology Cohort in WomenU01CA176726 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 2018 to 2025
$22.4M
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic researchU01HL145386 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO, MANSON, JOANN ELISABETH · 2019 to 2025
$17.8M
Infertility History and Chronic Disease ProfileR01HD096033 · NICHD · MICHIGAN STATE UNIVERSITY · PI RISINGER, JOHN IAN · 2019 to 2023
$3.4M
Predictors of Early MenopauseR01HD078517 · NICHD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI BERTONE-JOHNSON, ELIZABETH R · 2014 to 2018
$3.2M
Endometriosis, Infertility, and Risk of StrokeR21HD099623 · NICHD · UNIVERSITY OF ARIZONA · PI FARLAND, LESLIE V · 2020 to 2021
$442k
NCI NIH HHS U01 CA176726NHLBI NIH HHS U01 HL145386NICHD NIH HHS R01 HD078517NICHD NIH HHS R01 HD096033NICHD NIH HHS R21 HD099623
6 · The paper itself

Abstract

objectiveAnti-Müllerian hormone is a reliable measure of ovarian reserve associated with menopause timing and fertility. Previous studies have observed that individuals with endometriosis have lower anti-Müllerian hormone levels than those without. However, sample sizes have been small and information is limited regarding the long-term influence of endometriosis on anti-Müllerian hormone levels among the general population, which may have important implications for menopause timing and chronic disease risk.

methodsAmong 1961 premenopausal women in the Nurses' Health Study II who provided a blood sample and had not been pregnant in the last 6 months, we used generalized linear models to determine the association between laparoscopically-confirmed endometriosis and log-transformed plasma anti-Müllerian hormone level, adjusted for age (continuous and squared) and other potential confounding variables.

resultsParticipants were on average 40 years old (interquartile range 37-42 years) at blood draw. Women with endometriosis diagnosed prior to blood draw (n = 119) had a lower mean anti-Müllerian hormone level (1.6 ng/mL [SD = 2.3]) than women without known endometriosis (n = 1842) (2.8 ng/mL [SD = 3.0]). In multivariable adjusted models, women with endometriosis had 29.6 % lower anti-Müllerian hormone levels (95 % CI: -45.4, -9.2 %) than women without. This association was greater among women with a body mass index of 25 kg/m

conclusionsLower anti-Müllerian hormone levels in women with endometriosis may be one mechanism through which endometriosis influences risk of infertility, younger age at menopause, and cardiovascular disease.

Indexed as

EndometriosisInfertility, FemaleNursesAnti-Mullerian HormoneFemaleFertilityHumansPregnancyAnti-Mullerian HormoneAnti-Müllerian hormoneEndometriosisInfertility

Identifiers

PMID38489917
PMCPMC11186619
OpenAlexW4392792056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.