Evidence map›Paper›PMID 38488983›Full record

SynthesisEuropean geriatric medicine2024

Predictive performance of different measures of frailty (CFS, mFI-11, mFI-5) on postoperative adverse outcomes among colorectal cancer patients: a diagnostic meta-analysis.

Lingyu Ding, Qianwen Hua, Jiaojiao Xu, Jing Yang, Cui Yao

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lingyu DingDepartment of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Qianwen HuaDepartment of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Jiaojiao XuDepartment of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Jing YangDepartment of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Cui YaoDepartment of Colorectal Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. 1049089697@qq.com.

Funding

Jiangsu Agricultural Science and Technology Innovation Fund JSPH-NC-2022-25
6 · The paper itself

Abstract

purposeTo clarify the predictive performance of different measures of frailty, including Clinical Frailty Scale (CFS), 11-factor modified Frailty Index (mFI-11), and 5-factor modified Frailty Index (mFI-5), on adverse outcomes.

methodsPubMed, Embase, Web of Science, and other databases were retrieved from the inception of each database to June 2023. The pooled sensitivity, specificity, and the area under the summary receiver operating curve (SROC) values were analyzed to determine the predictive power of CFS, mFI-11, and mFI-5 for adverse outcomes.

resultsA total of 25 studies were included in quantitative synthesis. The pooled sensitivity values of CFS for predicting anastomotic leakage, total complications, and major complications were 0.39, 0.57, 0.45; pooled specificity values were 0.70, 0.58, 0.73; the area under SROC values were 0.58, 0.6, 0.66. The pooled sensitivity values of mFI-11 for predicting total complications and delirium were 0.38 and 0.64; pooled specificity values were 0.83 and 0.72; the area under SROC values were 0.64 and 0.74. The pooled sensitivity values of mFI-5 for predicting total complications, 30-day mortality, and major complications were 0.27, 0.54, 0.25; pooled specificity values were 0.82, 0.84, 0.81; the area under SROC values were 0.63, 0.82, 0.5.

conclusionThe results showed that CFS could predict anastomotic leakage, total complications, and major complications; mFI-11 could predict total complications and delirium; mFI-5 could predict total complications and 30-day mortality. More high-quality research is needed to support the conclusions of this study further.

Indexed as

Colorectal NeoplasmsDeliriumFrailtyAnastomotic LeakHumansPostoperative ComplicationsRisk AssessmentRisk FactorsAdverse outcomeFrailty assessmentMeta-analysisPredictive performance

Identifiers

PMID38488983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.