Evidence map›Paper›PMID 38488945›Full record

ArticleInternational ophthalmology2024

Plastic vs. glass: the effect of the synthetic material in contact with DMEK tissue during staining on endothelial cell loss.

Abdullah Al-Kaabi, Britta Gustavson, Abdulrahman Alotaibi, Ayman Aljohani, Julia Talajic, Johanna Choremis

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Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Abdullah Al-KaabiOphthalmology Department, University of Ottawa, Ottawa, ON, Canada.
Britta GustavsonOphthalmology Department, University of British Columbia, Vancouver, BC, Canada.
Abdulrahman AlotaibiOphthalmology Department, McGill University, Montreal, QC, Canada.
Ayman AljohaniOphthalmology Department, McGill University, Montreal, QC, Canada.
Julia TalajicOphthalmology Department, Faculty of Medicine, University of Montreal, CP 6128, Center-Ville Branch, Montreal, QC, H3C 3J7, Canada.
Johanna ChoremisOphthalmology Department, McGill University, Montreal, QC, Canada. johannachoremis@yahoo.ca.
McGill University · CAUniversité de Montréal · CAUniversity of British Columbia · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEndothelial cell loss (ECL) during Descemet membrane endothelial keratoplasty (DMEK) graft preparation has been shown to affect graft survival and the need for re-grafting. The purpose of this study was to quantitatively assess the impact of the plastic and glass mediums in contact with DMEK donor tissue during intra-operative graft staining on ECL.

methodsRetrospective study that included patients who underwent DMEK surgery between January 2019 and June 2021 at Hôpital Maisonneuve-Rosemont and the Jewish General Hospital in Montreal, Canada. DMEK grafts were stained with 0.06% Trypan blue ophthalmic solution (VisionBlue®, Dutch Ophthalmic, USA, Exeter, NH) for 120 s in either a plastic or glass medium prior to delivery into the recipient's eye. The ECL was compared between the two groups 12-30 months post-operatively.

resultsECL at 12-30 months was significantly less in the eyes that had received grafts stained in a plastic medium compared to those stained in a glass medium. Graft survival and re-bubbling was higher in the glass group however this difference was not statistically significant.

conclusionStaining of the DMEK graft in a plastic medium caused less ECL compared to the glass medium.

Indexed as

Descemet Stripping Endothelial KeratoplastyEndothelium, CornealCell CountCorneal Endothelial Cell LossDescemet MembraneEndothelial CellsGraft SurvivalHumansRetrospective StudiesStaining and LabelingTissue DonorsTrypan BlueTrypan BlueCorneal transplantDMEKEndothelial keratoplastyGlassPlastic

Identifiers

PMID38488945
OpenAlexW4392864878

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.