ArticleInternational urogynecology journal2024
Effect of Vaginal Microecological Alterations on Female Pelvic Organ Prolapse.
Article in International urogynecology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Vaginal Microbiota and Pelvic Floor Dysfunction: Mechanistic Insights and Therapeutic Implications.Medical science monitor : international medical journal of experimental and clinical research · 2026Review
- Collagen remodeling drives continence recovery: radiofrequency therapy ameliorates SUI via TGF-β1/Smad2 pathway activation - evidence from a rat model.Lasers in medical science · 2026Article
- Mobiluncus mulieris alters the transcriptomic profile of cervicovaginal epithelial cells, shedding light on molecular drivers of adverse reproductive outcomes.NPJ biofilms and microbiomes · 2025Article
- Association between TGF-β1 and β-catenin expression in the vaginal wall of patients with pelvic organ prolapse.Open life sciences · 2025Article
- Effects of platelet-rich plasma gel on vaginal microecology and stump healing and its underlying mechanism.Frontiers in medicine · 2025Article
- Review
- Cytokine modulation in pelvic organ prolapse and urinary incontinence: from molecular insights to therapeutic targets.Molecular medicine (Cambridge, Mass.) · 2024Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
introduction and hypothesisThe objective was to investigate the correlation between endogenous vaginal microecological alterations and female pelvic organ prolapse (POP).
methodsPatients who underwent vaginal hysterectomy were retrospectively analyzed as the POP group (n = 30) and the non-POP group (n = 30). The vaginal microbial metabolites and enzyme levels were tested using the dry chemoenzymatic method. The mRNA and protein expression were tested using real-time quantitative PCR and immunohistochemistry. SPSS version 25.0 and GraphPad Prism 8.0 were performed for statistical analysis.
resultsCompared with the non-POP group, the vaginal pH, H
conclusionsVaginal microecological dysbiosis affects the occurrence of female POP, which could be considered a novel therapeutic option.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.