Evidence map›Paper›PMID 38488875›Full record

ArticleWorld journal of urology2024

Preoperative urine culture with contaminants is not associated with increased risk for urinary tract infection after ureteroscopic stone treatment.

Willian Ito, Nicholas Choi, George Letner, Nicholas Genz, Dillon Prokop, Crystal Valadon, Mihaela E Sardiu, Holly Smith, Bristol B Whiles, Wilson R Molina

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Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Willian ItoDepartment of Urology, The University of Kansas Health System, Kansas City, KS, USA.
Nicholas ChoiSchool of Medicine, The University of Kansas, Kansas City, KS, USA.
George LetnerSchool of Medicine, The University of Kansas, Kansas City, KS, USA.
Nicholas GenzSchool of Medicine, The University of Kansas, Kansas City, KS, USA.
Dillon ProkopSchool of Medicine, The University of Kansas, Kansas City, KS, USA.
Crystal ValadonDepartment of Urology, The University of Kansas Health System, Kansas City, KS, USA.
Mihaela E SardiuDepartment of Biostatistics and Data Science, University of Kansas, 3901 Rainbow Boulevard, Mail Stop #3016, Kansas City, KS, 66160, USA.
Holly SmithDepartment of Biostatistics and Data Science, University of Kansas, 3901 Rainbow Boulevard, Mail Stop #3016, Kansas City, KS, 66160, USA.
Bristol B WhilesDepartment of Urology, The University of Kansas Health System, Kansas City, KS, USA.
Wilson R MolinaDepartment of Urology, The University of Kansas Health System, Kansas City, KS, USA. wmolina@kumc.edu.ORCID http://orcid.org/0000-0003-1379-237X
University of Kansas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to assess whether the presence of contaminants in the pre-operative urine culture (preop-UC) predicts postoperative urinary tract infection (postop-UTI) in patients undergoing elective ureteroscopy with laser lithotripsy.

methodsA retrospective chart review was performed from 01/2019 to 12/2021 examining patients with unilateral stone burden ≤ 2 cm who underwent ureteroscopy with laser lithotripsy and had a preop-UC within 3 months. Positive, negative, contaminated, and polymicrobial definitions for UCs were established in accordance with current guidelines. Patients with positive and polymicrobial cultures were excluded. Postop-UTI was defined as the presence of urinary symptoms and a positive UC within 30 days of the procedure. Multivariable logistic regression models were utilized to evaluate risk factors for contamination in the preop-UC and the risk of postop-UTI.

resultsA total of 201 patients met the inclusion-exclusion criteria. Preop-UC was negative in 153 patients and contaminated in 48 patients. Significant contaminant-related factors included female gender and increased BMI. Postop-UTI was diagnosed in 3.2% of patients with negative preop-UCs and 4.2% of patients with contaminants, with no difference between groups (p = 0.67). The regression model determined that the presence of contaminants in preop-UC failed to predict postop-UTI (OR 0.69, p = 0.64).

conclusionThe presence of contaminants in preop-UCs is not associated with an increased risk of postop-UTIs after ureteroscopy. Our study supports that contaminants in the preop-UC can be interpreted as a negative UC in terms of postop-UTI risk stratification. Preoperative antibiotics should not be prescribed for patients undergoing uncomplicated ureteroscopy for stone surgery in the setting of a contaminated preop-UC.

Indexed as

UreteroscopyUrinary Tract InfectionsAnti-Bacterial AgentsFemaleHumansPostoperative ComplicationsRetrospective StudiesUrinalysisAnti-Bacterial AgentsLithotripsyUreteroscopyUrinary tract infectionUrine culture

Identifiers

PMID38488875
OpenAlexW4392850772

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.