ReviewExpert review of cardiovascular therapy
Physical activity, exercise and adverse cardiovascular outcomes in individuals with pre-existing cardiovascular disease: a narrative review.
Review in Expert review of cardiovascular therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Exercise in Patients with Subclinical Atherosclerosis: Mechanisms, Clinical Evidence, and Practical Recommendations.Current atherosclerosis reports · 2026Review
- Increments in physical activity relate to reductions in tinnitus severity: a 2-year prospective observational study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Observational
- Association Between Hypertensive Disorders of Pregnancy, Lifestyle Factors, and Premature Cardiovascular Events.JACC. Advances · 2026Article
- Physical Activity in Arrhythmogenic Cardiomyopathy: From Trigger to Therapeutic Dilemma.Reviews in cardiovascular medicine · 2026Review
- Gender-Specific Trends and Determinants of Daily Smoking in Latvia (2009-2019): A Population-Based Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Degree of Food Processing and the Risk of Immune-Mediated Inflammatory Diseases: A Prospective Analysis of the SUN Cohort.Nutrients · 2026Article
- Real-World Associations Between Physical Activity, LDL Cholesterol, and Functional Performance in Primary Care: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Physical Activity and Clinically Defined Arterial Hypertension in Consecutive Primary Care Patients: A Real-World Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Beyond Autonomy, Competence, and Relatedness: A Comprehensive Scale for Basic Psychological Needs and Novelty in Exercise.Healthcare (Basel, Switzerland) · 2026Article
- Sex Differences in the Impact of Physical Activity Across the Spectrum of Cardiovascular Disease.Current cardiology reports · 2026Review
- Association Between Physical Activity, Sleep, and Hypertension Among U.S. Middle-Aged and Older Adults: Insights From NHANES.American journal of lifestyle medicine · 2026Article
- Physical Activity and Cardiovascular Health.Journal of diabetes research · 2026Review
- Exploring the role of place visitation big data on small area health measure estimation.Computational urban science · 2026Article
- Relationship between physical activity and cardiovascular disease in adults.American journal of translational research · 2026Article
- Accessibility and Availability of Healthcare Services in Jail Facilities among Persons Deprived of Liberty (PDL) in Dumaguete City, Philippines.Acta medica Philippina · 2026Article
- CCR2Frontiers in pharmacology · 2026Article
- Cardiovascular risk factor changes associated with six-year circuit training in older adults: a retrospective cohort analysis.Frontiers in aging · 2026Article
- Physical activity, air pollution, and incident long-term conditions: a prospective cohort study.BMC medicine · 2025Article
- Return-to-play in athletes with transvenous and subcutaneous implantable cardiac defibrillator: A meta-analysis.Journal of arrhythmia · 2025Article
- A Cross-Sectional Study of the Association of Neck Circumference and Cardiovascular Risk Among Market Women in Ghana.Health science reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe evidence supporting the cardiovascular health benefits of physical activity and/or exercise training is well-established. While the role of physical activity in primary prevention is unequivocal, its significance in secondary prevention (among those with preexisting cardiovascular disease) is less definitive. Though guidelines universally recommend physical activity as part of the secondary preventive strategy, the empirical evidence underpinning these recommendations is not as robust as that for primary prevention. AREAS COVERED: This review distills the body of available observational and interventional evidence on the relationship between physical activity, exercise, and adverse cardiovascular outcomes among those with preexisting cardiovascular disease. The postulated biologic mechanisms underlying the relationships, areas of prevailing uncertainty, and potential public health implications are also discussed. EXPERT OPINION: A physical activity level of 500 MET-min/week (equivalent to 150 min of moderate-intensity physical activity or 75 min of vigorous-intensity physical activity or an equivalent combination) may be a minimum requirement for patients with preexisting CVD. However, to reap the maximum benefits of physical activity and also minimize adverse effects, physical activity and/or exercise regimens should be tailored to unique factors such as individual's baseline physical activity habits, cardiovascular health status and the specific nature of their cardiovascular disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.