Evidence map›Paper›PMID 38488382›Full record

ReviewStroke2024

Treating Hypertension: Important for Heart Health, Fundamental for Brain Health.

Sanjula D Singh, Jasper R Senff, Cornelia M van Duijn, Jonathan Rosand

Open access · bronzeAbstract readReview
In one paragraph

Review in Stroke, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Isosakuranetin ameliorates hypertension in rats induced by L-NAME.Journal of pharmaceutical health care and sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Sanjula D SinghDepartment of Neurology, Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA (S.D.S., J.R.S., J.R.).ORCID 0000-0001-9304-8107
Jasper R SenffDepartment of Neurology, Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA (S.D.S., J.R.S., J.R.).ORCID 0009-0002-6540-480X
Cornelia M van DuijnNuffield Department of Population Health, Oxford, United Kingdom (C.M.v.D.).ORCID 0000-0002-2374-9204
Jonathan RosandDepartment of Neurology, Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA (S.D.S., J.R.S., J.R.).ORCID 0000-0002-1014-9138
Broad Institute · USNuffield Health · GB

Funding

Recurrent Hemorrhagic Stroke in Minority PopulationsR01NS093870 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI JONATHAN ROSAND, Amytis Towfighi · 2016 to 2026
$12.3M
NINDS NIH HHS R01 NS093870
6 · The paper itself

Abstract

The Brain Health crisis stands as one of humankind's most pressing threats, with age-related noncommunicable brain diseases, particularly stroke, and dementia, affecting hundreds of millions annually and jeopardizing the economic well-being of populations worldwide. Epidemiological studies indicate that ≈40% of dementia and 60% of stroke cases are attributable to modifiable risk factors. In this Comments and Opinions article, we underscore the pivotal role of blood pressure (BP) control in reducing suffering, enhancing economic well-being, and promoting healthy longevity for populations worldwide. Emphasizing that BP control is crucial for both brain and heart health, it advocates for heightened awareness, positioning hypertension as a primary focus for preventing dementia and stroke with potential global impact. Despite its significance, BP control encounters global challenges, with proportions of the population maintaining adequately controlled hypertension ranging from 23% to 90%. The World Health Organization estimated that 46% of the 1.28 billion people with hypertension are unaware of their elevated BP. Given the notable disparities in BP management, addressing BP management also contributes to combating significant health inequalities. The next time you are faced with a patient anxious about the prospect of experiencing a fate similar to a parent with dementia or a sister with a stroke, we suggest a straightforward answer for health care providers: start ensuring BP control. BP is a matter of brain health, and it is a matter of our economic future.

Indexed as

Antihypertensive AgentsBrainDementiaHypertensionStrokeBlood PressureHumansRisk FactorsAntihypertensive Agentsblood pressuredementiahypertensionrisk factorsstroke

Identifiers

PMID38488382
PMCPMC11039372
OpenAlexW4392848395

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.