Evidence map›Paper›PMID 38488367›Full record

ArticleStroke2024

Moving From CT to MRI Paradigm in Acute Ischemic Stroke: Feasibility, Effects on Stroke Diagnosis and Long-Term Outcomes.

Costanza Maria Rapillo, Vincent Dunet, Silvia Pistocchi, Alexander Salerno, Vincent Darioli, Bruno Bartolini, Steven David Hajdu, Patrik Michel, Davide Strambo

Open access · hybridAbstract read
In one paragraph

Article in Stroke, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

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  16. Delayed treatment of severe stroke: room for thrombectomy?European heart journal supplements : journal of the European Society of Cardiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Costanza Maria RapilloStroke Center, Service of Neurology, Department of Clinical Neuroscience (C.M.R., A.S., P.M., D.S.), University Hospital of Lausanne and University of Lausanne, Switzerland.ORCID 0000-0002-6380-6373
Vincent DunetNeuroradiology Unit, Service of Diagnostic and Interventional Radiology, Department of Medical Radiology (V. Dunet, S.P., B.B., S.D.H.), University Hospital of Lausanne and University of Lausanne, Switzerland.ORCID 0000-0002-9897-4561
Silvia PistocchiNeuroradiology Unit, Service of Diagnostic and Interventional Radiology, Department of Medical Radiology (V. Dunet, S.P., B.B., S.D.H.), University Hospital of Lausanne and University of Lausanne, Switzerland.
Alexander SalernoStroke Center, Service of Neurology, Department of Clinical Neuroscience (C.M.R., A.S., P.M., D.S.), University Hospital of Lausanne and University of Lausanne, Switzerland.ORCID 0000-0001-8494-5527
Vincent DarioliEmergency Department (V. Darioli) and Interventional Neuroradiological Unit, University Hospital of Lausanne and University of Lausanne, Switzerland.ORCID 0000-0002-1337-5296
Bruno BartoliniNeuroradiology Unit, Service of Diagnostic and Interventional Radiology, Department of Medical Radiology (V. Dunet, S.P., B.B., S.D.H.), University Hospital of Lausanne and University of Lausanne, Switzerland.ORCID 0000-0001-6055-0221
Steven David HajduNeuroradiology Unit, Service of Diagnostic and Interventional Radiology, Department of Medical Radiology (V. Dunet, S.P., B.B., S.D.H.), University Hospital of Lausanne and University of Lausanne, Switzerland.
Patrik MichelStroke Center, Service of Neurology, Department of Clinical Neuroscience (C.M.R., A.S., P.M., D.S.), University Hospital of Lausanne and University of Lausanne, Switzerland.ORCID 0000-0003-4954-7579
Davide StramboStroke Center, Service of Neurology, Department of Clinical Neuroscience (C.M.R., A.S., P.M., D.S.), University Hospital of Lausanne and University of Lausanne, Switzerland.ORCID 0000-0003-4429-2714
University Hospital of Lausanne · CHAzienda Ospedaliero-Universitaria Careggi · ITUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relative value of computed tomography (CT) and magnetic resonance imaging (MRI) in acute ischemic stroke (AIS) is debated. In May 2018, our center transitioned from using CT to MRI as first-line imaging for AIS. This retrospective study aims to assess the effects of this paradigm change on diagnosis and disability outcomes.

methodsWe compared all consecutive patients with confirmed diagnosis of AIS admitted to our center during the MRI-period (May 2018-August 2022) and an identical number of patients from the preceding CT-period (December 2012-April 2018). Univariable and multivariable analyses were performed to evaluate outcomes, including the number and delay of imaging exams, the rate of missed strokes, stroke mimics treated with thrombolysis, undetermined stroke mechanisms, length of hospitalization, and 3-month disability.

resultsThe median age of the 2972 included patients was 76 years (interquartile range, 65-84), and 46% were female. In the MRI-period, 80% underwent MRI as first acute imaging. The proportion of patients requiring a second acute imaging modality for diagnostic ± revascularization reasons increased from 2.1% to 5% (

conclusionsA paradigm shift from CT to MRI as first-line imaging for AIS seems feasible in a comprehensive stroke center, with a minimally increased delay to imaging in thrombolysis candidates. MRI was associated with reduced thrombolysis rates of stroke mimics and subacute neuroimaging needs.

Indexed as

Ischemic StrokeMagnetic Resonance ImagingTomography, X-Ray ComputedAgedAged, 80 and overFeasibility StudiesFemaleHumansMaleRetrospective StudiesThrombolytic Therapyintracranial hemorrhageischemic strokeneuroimagingworkflow

Identifiers

PMID38488367
PMCPMC11045552
OpenAlexW4392848374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.