Evidence map›Paper›PMID 38487724›Full record

ReviewFrontiers in oncology2024

Role of long non-coding RNA in chemoradiotherapy resistance of nasopharyngeal carcinoma.

Yang Yang, QuPing Yuan, Weijian Tang, Ya Ma, JingYan Duan, GuoNing Yang, Yuan Fang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. [Progress of scRNA-seq technology in nasopharyngeal carcinoma research].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yang YangOtorhinolaryngology Head and Neck Surgery, Baoshan People's Hospital, Baoshan, Yunnan, China.
QuPing YuanPuer People's Hospital, Department of Critical Medicine, PuEr, Yunnan, China.
Weijian TangQueen Mary School of Nanchang University, Nanchang University, Nanchang, China.
Ya MaOtorhinolaryngology Head and Neck Surgery, Baoshan People's Hospital, Baoshan, Yunnan, China.
JingYan DuanOtorhinolaryngology Head and Neck Surgery, Baoshan People's Hospital, Baoshan, Yunnan, China.
GuoNing YangOtorhinolaryngology Head and Neck Surgery, Baoshan People's Hospital, Baoshan, Yunnan, China.
Yuan FangDepartment of Organ Transplantation, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Baoshan College · CNKunming Medical University · CNNanchang University · CNPuer University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is a malignant tumor originating from the nasopharyngeal epithelial cells. Common treatment methods for NPC include radiotherapy, chemotherapy, and surgical intervention. Despite these approaches, the prognosis for NPC remains poor due to treatment resistance and recurrence. Hence, there is a crucial need for more comprehensive research into the mechanisms underlying treatment resistance in NPC. Long non coding RNAs (LncRNAs) are elongated RNA molecules that do not encode proteins. They paly significant roles in various biological processes within tumors, such as chemotherapy resistance, radiation resistance, and tumor recurrence. Recent studies have increasingly unveiled the mechanisms through which LncRNAs contribute to treatment resistance in NPC. Consequently, LncRNAs hold promise as potential biomarkers and therapeutic targets for diagnosing NPC. This review provides an overview of the role of LncRNAs in NPC treatment resistance and explores their potential as therapeutic targets for managing NPC.

Indexed as

drug resistancelong noncoding RNAsnasopharyngeal carcinomaradiation resistancerecurrence

Identifiers

PMID38487724
PMCPMC10937456
OpenAlexW4392292198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.