Evidence map›Paper›PMID 38487694›Full record

ArticleBiological imaging2023

Performant web-based interactive visualization tool for spatially-resolved transcriptomics experiments.

Chaichontat Sriworarat, Annie Nguyen, Nicholas J Eagles, Leonardo Collado-Torres, Keri Martinowich, Kristen R Maynard, Stephanie C Hicks

Abstract read
In one paragraph

Article in Biological imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  14. escheR: Unified multi-dimensional visualizations with Gestalt principles.bioRxiv : the preprint server for biology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chaichontat SriworaratDepartment of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-1917-3409
Annie NguyenLieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.ORCID https://orcid.org/0000-0003-3842-6923
Nicholas J EaglesLieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-9808-5254
Leonardo Collado-TorresLieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.ORCID https://orcid.org/0000-0003-2140-308X
Keri MartinowichDepartment of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-5237-0789
Kristen R MaynardDepartment of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0003-0031-8468
Stephanie C HicksDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-7858-0231

Funding

Laminar dissection of cortical human brain gene expression in neuropsychiatric disordersR01MH126393 · NIMH · LIEBER INSTITUTE, INC. · PI MARTINOWICH, KERI · 2021 to 2025
$3.9M
Registration of spatial gene expression in key nodes of reward-related circuitry in the human brainR01DA053581 · NIDA · LIEBER INSTITUTE, INC. · PI MARTINOWICH, KERI · 2021 to 2025
$3.7M
Spatial registration of gene expression in the human brainU01MH122849 · NIMH · LIEBER INSTITUTE, INC. · PI MARTINOWICH, KERI · 2020 to 2021
$1.7M
NIDA NIH HHS R01 DA053581NIMH NIH HHS R01 MH126393NIMH NIH HHS U01 MH122849
6 · The paper itself

Abstract

High-resolution and multiplexed imaging techniques are giving us an increasingly detailed observation of a biological system. However, sharing, exploring, and customizing the visualization of large multidimensional images can be a challenge. Here, we introduce Samui, a performant and interactive image visualization tool that runs completely in the web browser. Samui is specifically designed for fast image visualization and annotation and enables users to browse through large images and their selected features within seconds of receiving a link. We demonstrate the broad utility of Samui with images generated with two platforms: Vizgen MERFISH and 10x Genomics Visium Spatial Gene Expression. Samui along with example datasets is available at https://samuibrowser.com.

Indexed as

georeferencinginteractive image viewermulti-dimensional imagesingle-cell transcriptomicsspatially resolved transcriptomicsweb-based browser

Identifiers

PMID38487694
PMCPMC10936372

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.