Evidence map›Paper›PMID 38487652›Full record

ArticleGeneral hospital psychiatry

30-year Cardiovascular Disease Risk for Young Adults with Serious Mental Illness.

Kathleen M Miley, Stephanie A Hooker, A Lauren Crain, Patrick J O'Connor, Jacob L Haapala, David J Bond, Rebecca C Rossom

Open access · greenAbstract read
In one paragraph

Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kathleen M MileyHealthPartners Institute. 8170 33 Ave S., Minneapolis, Minnesota 55425, USA.
Stephanie A HookerHealthPartners Institute. 8170 33 Ave S., Minneapolis, Minnesota 55425, USA.
A Lauren CrainHealthPartners Institute. 8170 33 Ave S., Minneapolis, Minnesota 55425, USA.
Patrick J O'ConnorHealthPartners Institute. 8170 33 Ave S., Minneapolis, Minnesota 55425, USA.
Jacob L HaapalaHealthPartners Institute. 8170 33 Ave S., Minneapolis, Minnesota 55425, USA.
David J BondJohns Hopkins University, Department of Psychiatry and Behavioral Sciences. 600 N Wolfe St., Baltimore, Maryland 21205, USA.
Rebecca C RossomHealthPartners Institute. 8170 33 Ave S., Minneapolis, Minnesota 55425, USA.
HealthPartners · USUniversity of Minnesota Medical Center · USJohns Hopkins University · US

Funding

SSRI's and SuicidalityU19MH092201 · NIMH · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIMON, GREGORY E. · 2010 to 2018
$19.5M
NIMH NIH HHS U19 MH092201
6 · The paper itself

Abstract

Objective: To estimate 30-year CVD risk and modifiable risk factors in young adults with serious mental illness (SMI) versus those without, and assess variations in CVD risk by race, ethnicity, and sex. Method: In this cross-sectional study, we estimated and compared the Framingham 30-year CVD risk score and individual modifiable CVD risk factors in young adult (20-39 years) primary care patients with and without SMI at two US healthcare systems (January 2016-Septemeber 2018). Interaction terms assessed whether the SMI-risk association differed across demographic groups. Results: Covariate-adjusted 30-year CVD risk was significantly higher for those with (n=4228) versus those without (n=155,363) SMI (RR 1.28, 95% CI [1.26, 1.30]). Patients with SMI had higher rates of hypertension (OR 2.02 [1.7, 2.39]), diabetes (OR 3.14 [2.59, 3.82]), obesity (OR 1.93 [1.8, 2.07]), and smoking (OR 4.94 [4.6, 5.36]). The increased 30-year CVD risk associated with SMI varied significantly by race and sex: there was an 8% higher risk in Black compared to White patients (RR 1.08, [1.04, 1.12]) and a 9% lower risk in men compared to women (RR 0.91 [0.88, 0.94]). Conclusions: Young adults with SMI are at increased 30-year risk of CVD, and further disparities exist for Black individuals and women.

Indexed as

Cardiovascular DiseasesHypertensionMental DisordersCross-Sectional StudiesEthnicityFemaleHumansMaleRisk FactorsYoung Adultbipolar disordercardiometabolic disordershealth disparitiesschizoaffective disorderschizophrenia

Identifiers

PMID38487652
PMCPMC10936711
OpenAlexW4387842154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.