Evidence map›Paper›PMID 38487622›Full record

ArticlePhysics and imaging in radiation oncology2024

Evaluation of a cone-beam computed tomography system calibrated for accurate radiotherapy dose calculation.

Marta Bogowicz, Didier Lustermans, Vicki Trier Taasti, Colien Hazelaar, Frank Verhaegen, Gabriel Paiva Fonseca, Wouter van Elmpt

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  10. Maintaining quality of scientific peer-review and publishing inPhysics and imaging in radiation oncology · 2026
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  19. The feasibility of CT simulation-free adaptive radiation therapy.Journal of applied clinical medical physics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marta BogowiczDepartment of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Didier LustermansDepartment of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Vicki Trier TaastiDepartment of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Colien HazelaarDepartment of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Frank VerhaegenDepartment of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Gabriel Paiva FonsecaDepartment of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Wouter van ElmptDepartment of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Dose calculation on cone-beam computed tomography (CBCT) images has been less accurate than on computed tomography (CT) images due to lower image quality and discrepancies in CT numbers for CBCT. As increasing interest arises in offline and online re-planning, dose calculation accuracy was evaluated for a novel CBCT imager integrated into a ring gantry treatment machine. Materials and methods: The new CBCT system allowed fast image acquisition (5.9 s) by using new hardware, including a large-size flat panel detector, and incorporated image-processing algorithms with iterative reconstruction techniques, leading to accurate CT numbers allowing dose calculation. In this study, CBCT- and CT-based dose calculations were compared based on three anthropomorphic phantoms, after CBCT-to-mass-density calibration was performed. Six plans were created on the CT scans covering various target locations and complexities, followed by CBCT to CT registrations, copying of contours, and re-calculation of the plans on the CBCT scans. Dose-volume histogram metrics for target volumes and organs-at-risk (OARs) were evaluated, and global gamma analyses were performed. Results: Target coverage differences were consistently below 1.2 %, demonstrating the agreement between CT and re-calculated CBCT dose distributions. Differences in D Conclusions: This study demonstrated comparable results between dose calculations performed on CBCT and CT acquisitions. The new CBCT system with enhanced image quality and CT number accuracy opens possibilities for off-line and on-line re-planning.

Indexed as

Cone-beam computed tomographyCT number accuracyDose calculationImage qualityMetal artifact reductionRadiotherapy

Identifiers

PMID38487622
PMCPMC10937948

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.