Evidence map›Paper›PMID 38487558›Full record

ArticleFrontline gastroenterology2024

Dedicated service for Barrett's oesophagus surveillance endoscopy yields higher dysplasia detection and guideline adherence in a non-tertiary setting in the UK: a 5-year comparative cohort study.

Elizabeth Ratcliffe, James Britton, Harika Yalamanchili, Izabela Rostami, Syed Mujtaba Hasnain Nadir, Mohamed Korani, Ikedichukwu Eruchie, Muhammad Awais Wazirdin, Neeraj Prasad, Shaheen Hamdy and 2 more

Open access · greenAbstract read
In one paragraph

Article in Frontline gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Elizabeth RatcliffeGastroenterology department, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK.ORCID 0000-0001-6521-2133
James BrittonGastroenterology department, Northern Care Alliance NHS Trust, Salford, UK.
Harika YalamanchiliGastroenterology department, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK.
Izabela RostamiGastroenterology department, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK.
Syed Mujtaba Hasnain NadirGastroenterology department, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK.
Mohamed KoraniGastroenterology department, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK.
Ikedichukwu EruchieGastroenterology department, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK.
Muhammad Awais WazirdinGastroenterology department, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK.
Neeraj PrasadGastroenterology department, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK.
Shaheen HamdyDivision of Diabetes, Endocrinology and Gastroenterology Faculty of Biology, Medicine and Health School of Medical Sciences, University of Manchester, Manchester, UK.
John McLaughlinDivision of Diabetes, Endocrinology and Gastroenterology Faculty of Biology, Medicine and Health School of Medical Sciences, University of Manchester, Manchester, UK.ORCID 0000-0001-6158-5135
Yeng AngDivision of Diabetes, Endocrinology and Gastroenterology Faculty of Biology, Medicine and Health School of Medical Sciences, University of Manchester, Manchester, UK.
Wrightington, Wigan and Leigh NHS Foundation Trust · GBUniversity of Manchester · GBNorthern Health and Social Care Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Barrett's oesophagus (BO) endoscopic surveillance is performed to varying quality, dedicated services may offer improved outcomes. This study compares a dedicated BO service to standard care, specifically dysplasia detection rate (DDR), guideline adherence and use of advanced imaging modalities in a non-tertiary setting. Design/method: 5-year retrospective comparative cohort study comparing a dedicated BO endoscopy service with surveillance performed on non-dedicated slots at a non-tertiary centre in the UK. All adult patients undergoing BO surveillance between 1 March 2016 and 1 March 2021 were reviewed and those who underwent endoscopy on a dedicated BO service run by endoscopists with training in BO was compared with patients receiving their BO surveillance on any other endoscopy list. Endoscopy reports, histology results and clinic letters were reviewed for DDR and British society of gastroenterology guideline adherence. Results: 921 BO procedures were included (678 patients). 574 (62%) endoscopies were on a dedicated BO list vs 348 (38%) on non-dedicated.DDR was significantly higher in the dedicated cohort 6.3% (36/568) vs 2.7% (9/337) (p=0.014). Significance was sustained when cases with indefinite for dysplasia were excluded: 4.9% 27/533 vs 0.9% 3/329 (p=0.002). Guideline adherence was significantly better on the dedicated endoscopy lists.Factors associated with dysplasia detection in regression analysis included visible lesion documentation (p=0.036), use of targeted biopsies (p=<0.001), number of biopsies obtained (p≤0.001). Conclusions: A dedicated Barrett's service showed higher DDR and guideline adherence than standard care and may be beneficial pending randomised trial data.

Indexed as

BARRETT'S METAPLASIABARRETT'S OESOPHAGUSDYSPLASIAENDOSCOPYGASTROINTESINAL ENDOSCOPY

Identifiers

PMID38487558
PMCPMC10935534
OpenAlexW4385737079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.