Evidence map›Paper›PMID 38487357›Full record

ArticleNeuro-ophthalmology (Aeolus Press)2024

Thrombolytic Therapy for Central Retinal Artery Occlusion in an Academic Multi-Site Stroke Centre.

Nour Alhayek, Jacob M Sobczak, Aimen Vanood, Cumara B O'Carroll, Bart M Demaerschalk, John Chen, Oana M Dumitrascu

Open access · greenAbstract read
In one paragraph

Article in Neuro-ophthalmology (Aeolus Press), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Effectiveness and safety of intravenous thrombolysis for non-arteritic central retinal artery occlusion: A GRADE-assessed meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nour AlhayekDepartment of Neurology, Mayo Clinic College of Medicine and Science, Scottsdale, Arizona, USA.
Jacob M SobczakDepartment of Neurology, Mayo Clinic College of Medicine and Science, Scottsdale, Arizona, USA.
Aimen VanoodDepartment of Neurology, Mayo Clinic College of Medicine and Science, Scottsdale, Arizona, USA.
Cumara B O'CarrollDepartment of Neurology, Mayo Clinic College of Medicine and Science, Scottsdale, Arizona, USA.
Bart M DemaerschalkDepartment of Neurology, Mayo Clinic College of Medicine and Science, Scottsdale, Arizona, USA.
John ChenDepartment of Ophthalmology and Neurology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0003-3644-7528
Oana M DumitrascuDepartment of Neurology, Mayo Clinic College of Medicine and Science, Scottsdale, Arizona, USA.ORCID https://orcid.org/0000-0003-2033-449X
Mayo Clinic in Arizona · USMayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central retinal artery occlusion (CRAO) is a subtype of acute ischaemic stroke leading to severe visual loss. A recent American Heart Association scientific statement proposed time-windows for thrombolysis in CRAO similar to acute ischaemic cerebral strokes. We aimed to review our academic multi-site stroke centre experience with intravenous (IVT) and intra-arterial thrombolysis (IAT) in CRAO between 1997 and 2022. Demographic, clinical characteristics, thrombolysis timeline, concurrent therapies, complications, and 3-month follow-up visual acuity (VA) were collected. The thrombolysed cohort follow-up VA was compared with an age, gender and baseline VA matched cohort of CRAO patients that received conservative therapies. Thrombolytic therapy was administered to 3.55% (

Indexed as

Retinal artery occlusionthrombolytic therapyvisual acuity

Identifiers

PMID38487357
PMCPMC10936677
OpenAlexW4390579813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.