Evidence map›Paper›PMID 38487144›Full record

ArticleCureus2024

Adverse Effects of Cancer Treatment in Patients With Cervical Cancer.

Mahesh Palagudi, Sneha Para, Nagasree Golla, Krishna Chaitanya Meduri, Sai Praneeth Duvvuri, Yethindra Vityala, Deepika Chowdary Sajja, Ujwala Damineni

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Quality of Life of Emirati Women with Cervical Cancer Using EORTC QLQ-30 and CX24: A First Look in the UAE.International journal of environmental research and public health · 2025
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Mahesh PalagudiDepartment of General Medicine, P.E.S. Institute of Medical Sciences and Research, Kuppam, IND.
Sneha ParaDepartment of General Medicine, Maheshwara Medical College and Hospital, Hyderabad, IND.
Nagasree GollaDepartment of General Medicine, I. K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, KGZ.
Krishna Chaitanya MeduriDepartment of General Medicine, Maheshwara Medical College and Hospital, Hyderabad, IND.
Sai Praneeth DuvvuriDepartment of General Medicine, Maheshwara Medical College and Hospital, Hyderabad, IND.
Yethindra VityalaDepartment of Research, AJ Research Centre, AJ Institute of Medical Sciences and Research Centre, Mangalore, IND.
Deepika Chowdary SajjaDepartment of General Medicine, Santhiram Medical College, Tirupati, IND.
Ujwala DamineniDepartment of General Medicine, Maheshwara Medical College and Hospital, Hyderabad, IND.
Deccan College of Medical Sciences · INInternational University of Kyrgyzstan · KGK.S. Hegde Hospital · INKyrgyz State Medical Academy · KG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn lower- to middle-income countries such as India, the literature on the adverse effects (AEs) of cancer treatment in patients with cervical cancer is very limited. This knowledge gap provides an opportunity to investigate and improve the quality of life for women with cervical cancer.

objectiveThe purpose of this study was to assess the AEs of various cancer treatment combinations in patients with cervical cancer.

methodsThis observational, retrospective study analysed 1,030 women with cervical cancer, with a descriptive cross-sectional design, based on a review of medical records from patients who were followed up during the morbidity consultation conducted by a multidisciplinary team of doctors. The AEs of cancer treatment for women with cervical cancer were recorded in these medical records between October 14, 2019, and November 21, 2022, at 10 major public tertiary hospitals in India.

resultsThis study analysed 1,030 women with cervical cancer aged between 21 and 80 years (mean age: 48.8 ± 13.9 years; p=0.30). Patients between the ages of 36-50 years reported the most AEs (30.2%; 95% confidence interval (CI): 29.1-32.8) among other age groups. Combined radiation therapy and chemotherapy (CT) was the type of cancer treatment in which there were more AEs, presenting in 56.0% (95% CI: 55-60.1) of patients. Adverse effects associated with the gastrointestinal system were observed in the majority (92.5%, 95% CI: 90.2-96.9) of cervical cancer patients.

conclusionExposure to different cancer treatments, particularly combination therapy, induces AEs in patients during and after cervical cancer treatment.

Indexed as

adverse effectsbrachytherapycervical cancerchemotherapyradiation therapy

Identifiers

PMID38487144
PMCPMC10938271
OpenAlexW4391780523

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.