Evidence map›Paper›PMID 38486988›Full record

ArticleActa pharmaceutica Sinica. B2024

The effect of lengths of branched-chain fatty alcohols on the efficacy and safety of docetaxel-prodrug nanoassemblies.

Shuo Wang, Tian Liu, Yuetong Huang, Chaoying Du, Danping Wang, Xiyan Wang, Qingzhi Lv, Zhonggui He, Yinglei Zhai, Bingjun Sun and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Shuo WangWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
Tian LiuWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
Yuetong HuangWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
Chaoying DuWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
Danping WangSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xiyan WangWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
Qingzhi LvSchool of Pharmacy, Binzhou Medical University, Binzhou 256600, China.
Zhonggui HeWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
Yinglei ZhaiSchool of Medical Devices, Shenyang Pharmaceutical University, Shenyang 110016, China.
Bingjun SunWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
Jin SunWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
Shenyang Pharmaceutical University · CNBinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The self-assembly prodrugs are usually consisted of drug modules, activation modules, and assembly modules. Keeping the balance between efficacy and safety by selecting suitable modules remains a challenge for developing prodrug nanoassemblies. This study designed four docetaxel (DTX) prodrugs using disulfide bonds as activation modules and different lengths of branched-chain fatty alcohols as assembly modules (C

Indexed as

Branched-chain fatty alcoholsDisulfide bondDocetaxelEfficacyNanoassembliesProdrugsSafetySelf-assembly

Identifiers

PMID38486988
PMCPMC10934334
OpenAlexW4387223600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.