Evidence map›Paper›PMID 38486977›Full record

ArticleFunction (Oxford, England)2024

Phosphodiesterases Mediate the Augmentation of Myogenic Constriction by Inhibitory G Protein Signaling and is Negatively Modulated by the Dual Action of RGS2 and 5.

Bo Sun, Nia Smith, Alethia J Dixon, Patrick Osei-Owusu

Open access · goldAbstract read
In one paragraph

Article in Function (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bo SunDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Nia SmithDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Alethia J DixonDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Patrick Osei-OwusuDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Case Western Reserve University · USUniversity School · US

Funding

In Vivo Mechanisms of Integrated G protein Signaling Regulation by RGS ProteinsR01HL139754 · NHLBI · DREXEL UNIVERSITY · PI OSEI-OWUSU, PATRICK · 2018 to 2021
$1.6M
Mechanisms of Impaired Renal Hemodynamics after Spinal Cord InjuryR56DK132859 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI OSEI-OWUSU, PATRICK · 2022 to 2022
$100k
NHLBI NIH HHS R01 HL139754NIDDK NIH HHS R56 DK132859
6 · The paper itself

Abstract

G protein regulation by regulators of G protein signaling (RGS) proteins play a key role in vascular tone maintenance. The loss of G

Indexed as

DopamineSignal TransductionAnimalsConstrictionGTP-Binding ProteinsHemodynamicsMiceDopamineGTP-Binding ProteinscAMPG protein signalingmyogenic responseRGS proteinsuterine hemodynamics

Identifiers

PMID38486977
PMCPMC10935470
OpenAlexW4391049051

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.