ArticleThe Journal of clinical endocrinology and metabolism2024
Age-related Curves of AMH Using the Gen II, the picoAMH, and the Elecsys Assays in Women With Polycystic Ovary Syndrome.
Article in The Journal of clinical endocrinology and metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Bibliometric analysis of the research on anti-Müllerian hormone and polycystic ovary syndrome: current status, hotspots, and trends.Frontiers in reproductive health · 2025Pooled it
- Optimising metformin use in polycystic ovary syndrome (MET-PCOS): study protocol for a double-blind randomised controlled trial.BMJ open · 2026Article
- Evaluating the PCOS risk algorithm (PriskA): a pilot study.Journal of ovarian research · 2026Article
- Transvaginal ultrasound combined with serum anti-Müllerian hormone, follicle-stimulating hormone, and luteinizing hormone in the evaluation of ovarian reserve function in infertile patients.American journal of translational research · 2026Article
- Age-Independent Serum AMH Levels in Women With PCOS Defined by the 2018 Evidence-Based Guideline Diagnostic Criteria: A Cross-Sectional Study.Clinical endocrinology · 2025Article
- Approach to the Patient: Diagnostic Challenges in the Workup for Polycystic Ovary Syndrome.The Journal of clinical endocrinology and metabolism · 2025Review
- Article
- Age-related Curves of AMH Using the Gen II, the picoAMH, and the Elecsys Assays in Women With Polycystic Ovary Syndrome.The Journal of clinical endocrinology and metabolism · 2024Article
- Anti-Müllerian hormone a surrogate of follicular fluid oxidative stress in polycystic ovary syndrome?Frontiers in cell and developmental biology · 2024Article
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextSeveral challenges still exist to adopt the anti-müllerian hormone (AMH) as a marker of polycystic ovary morphology, as included in the recently updated international guideline. Although different evaluations of age- and assay-specific reference ranges have been published in the past few years, these studies have mainly been conducted in normo-ovulatory or infertile women.
objectiveTo develop an age-specific percentile distribution of AMH in patients with polycystic ovary syndrome (PCOS) measured by 3 different assays.
designRetrospective cross-sectional study. PATIENTS: A total of 2725 women aged 20 to 40 years with PCOS diagnosis were included.
interventionsSerum AMH measurement by the Gen II (Beckman Coulter), the picoAMH (Ansh Labs), and the Elecsys (Roche) assays.
main outcome measuresAge-specific percentile curves for all the assays and correlations between AMH, clinical, hormonal, and ultrasound characteristics.
resultsAge-related nomograms for the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles of AMH were calculated using the Lambda-Mu-Sigma method for all the assays. AMH levels were significantly different between PCOS phenotypes. AMH levels were positively correlated to LH, LH/FSH ratio, testosterone, androstenedione, free androgen index, mean follicular number, and mean ovarian volume.
conclusionTo our knowledge, this is the first study reporting age-specific percentile nomograms of serum AMH levels measured by the Gen II, the picoAMH, and the Elecsys assays in a large population of women with PCOS. These findings may help to interpret AMH levels in patients with PCOS and facilitate the use of AMH as a diagnostic tool across age ranges.
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