Evidence map›Paper›PMID 38486371›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2024

Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions.

Guy Hajj-Boutros, Andréa Faust, John Muscedere, Perry Kim, Naji Abumrad, Stéphanie Chevalier, Mylene Aubertin-Leheudre, Howard Bergman, Dawn Bowdish, Jessica Burford and 22 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Foundations and Strategic Vision of the Canadian Translational Geroscience Network.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Guy Hajj-BoutrosDepartment of Medicine, McGill University and Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.
Andréa FaustDepartment of Medicine, McGill University and Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.
John MuscedereCanadian Frailty Network, Kingston, Ontario, Canada.
Perry KimCanadian Frailty Network, Kingston, Ontario, Canada.
Naji AbumradDivision of Surgical Oncology and Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Stéphanie ChevalierSchool of Human Nutrition, McGill University, Montréal, Québec, Canada.ORCID 0000-0002-8497-1570
Mylene Aubertin-LeheudreDépartement des Sciences de l'Activité Physique, Faculté des Sciences, Université du Québec à Montréal, Montréal, Québec, Canada.
Howard BergmanSchouela Centre of Excellence for Sustainable Health of Seniors (Schouela CEDurable), Montreal, Québec, Canada.
Dawn BowdishDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Jessica BurfordArthur Labatt Family School of Nursing, Faculty of Health Science, Western University, London, Ontario, Canada.
Stacy Carrington-LawrenceDivision of Aging Biology, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
Hélène CôtéDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
David E DaweDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Philipe de Souto BarretoIHU HealthAge, CERPOP UMR 1295, Toulouse, France.
Colin FarrellyDepartment of Political Studies, Queen's University, Kingston, Ontario, Canada.ORCID 0000-0002-3889-3778
Robert FowlerDepartment of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Gilles GouspillouDépartement des Sciences de l'Activité Physique, Faculté des Sciences, Université du Québec à Montréal, Montréal, Québec, Canada.
Lea HarringtonDepartment of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Sofie LautrupDepartment of Clinical Molecular Biology, University of Oslo, and Akershus University Hospital, Lørenskog, Norway.ORCID 0000-0002-6632-7853
Susan HowlettDepartment of Medicine (Geriatric Medicine), Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0001-5351-6308
Mahdi ImaniAustralian Institute for Musculoskeletal Science (AIMSS), Geroscience and Osteosarcopenia Research Program, University of Melbourne and Western Health, St Albans, Victoria, Australia.
James KirklandMayo Clinic, Rochester, Minnesota, USA.
George KuchelUConn Center on Aging, University of Connecticut School of Medicine, UConn Health, Farmington, Connecticut, USA.
Frédérick A MalletteDepartment of Medicine, Université de Montréal, Montréal, Québec, Canada.
José A MoraisDepartment of Medicine, McGill University and Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.ORCID 0000-0001-9366-6626
John C NewmanBuck Institute for Research on Aging, San Francisco, California, USA.ORCID 0000-0002-8455-0100
Daryl PullmanFaculty of Medicine, Memorial University, St. John's, Newfoundland, Canada.
Felipe SierraHevolution Foundation, Riyadh, Saudi Arabia.
Jeremy Van RaamsdonkResearch Institute of the McGill University Health Centre, Montreal, Quebec, Canada.ORCID 0000-0001-8376-9605
Jennifer WattDepartment of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.ORCID 0000-0002-5296-6013
Rebecca Jane RylettDepartment of Physiology and Pharmacology, Western University, London, Ontario, Canada.
Gustavo DuqueDepartment of Medicine, McGill University and Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.ORCID 0000-0001-8126-0637

Funding

Research Education ComponentP30AG067988 · NIA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Richard H Fortinsky, GEORGE A KUCHEL · 2021 to 2026
$9.5M
Canadian Frailty NetworkCIHRDivision of Geriatric MedicineHevolution FoundationInstitute of AgeingMcGill UniversityMcGill University Health CentreNIA NIH HHS P30 AG067988Schouela CEDurable Centre of Excellence for Sustainable Health of Seniors
6 · The paper itself

Abstract

The inaugural Canadian Conferences on Translational Geroscience were held as 2 complementary sessions in October and November 2023. The conferences explored the profound interplay between the biology of aging, social determinants of health, the potential societal impact of geroscience, and the maintenance of health in aging individuals. Although topics such as cellular senescence, molecular and genetic determinants of aging, and prevention of chronic disease were addressed, the conferences went on to emphasize practical applications for enhancing older people's quality of life. This article summarizes the proceeding and underscores the synergy between clinical and fundamental studies. Future directions highlight national and global collaborations and the crucial integration of early-career investigators. This work charts a course for a national framework for continued innovation and advancement in translational geroscience in Canada.

Indexed as

GeriatricsTranslational Research, BiomedicalAgedAgingCanadaForecastingHumansQuality of LifeAgingAnimal studiesClinical trialsGeroscienceTranslational Research

Identifiers

PMID38486371
PMCPMC11167488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.