Evidence map›Paper›PMID 38486359›Full record

Trial reportThe Gerontologist2024

The Effects of Exergame Telerehabilitation in Persons With Subjective Cognitive Decline.

Dereck L Salisbury, Keenan A Pituch, Fang Yu

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Gerontologist, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04311736 (Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04311736 naunknown statusnot on this map

Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults (The Exergame Study)

TypeinterventionalSponsorMoai Technologies LLCRan2019 to 2021Enrolled96ConditionsMild Cognitive Impairment, Exercise TrainingArmsExergame, Cycling, Stretching
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Dereck L SalisburySchool of Nursing, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-0117-2643
Keenan A PituchEdison College of Nursing and Health Innovation, Arizona State University, Phoenix, Arizona, USA.
Fang YuEdison College of Nursing and Health Innovation, Arizona State University, Phoenix, Arizona, USA.
Arizona State University · USUniversity of Minnesota · US

Funding

Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer’s in at-risk Older AdultsR44AG055176 · NIA · MOAI TECHNOLOGIES, LLC · PI PLOCHER, TOM, YU, FANG · 2016 to 2019
$1.7M
NIA NIH HHS 4R44AG055176-02NIA NIH HHS R44 AG055176NIH HHS
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe primary aim of this Stage IB randomized controlled trial (RCT) was to test the preliminary effects of a dual-task exergaming telerehabilitation intervention on cognition and aerobic fitness, compared to aerobic exercise (AEx) only and attention control (stretching) in older adults with subjective cognitive decline. RESEARCH DESIGN AND

methodsThis RCT randomized 39 participants on a 2:1:1 allocation ratio to supervised exergame (n = 20), AEx (n = 11), and stretching (n = 8) for 12 weeks. The dual-task exergaming was concurrent moderate-intensity cycling and BrainFitRx cognitive telerehabilitation. Cognition was assessed by NIH Toolbox Cognitive Battery and aerobic fitness by 6-minute walk test (6MWT) and shuttle walk test.

resultsThe participants were 74.6 (7.4) years old and 69% were female. The effect of time was significant, F(1, 23.9) = 13.16, p = .001, for the Fluid Composite score, and significant within-group changes were seen for the exergame group, t(14.08) = 2.53, p = .024, d = 0.33. Between-group changes did not reach significant levels for any cognitive test. Between-group changes for the 6MWT were not significant. DISCUSSION AND IMPLICATIONS: The exergame participants further improved their fluid cognition, whereas the AEx and stretching groups did not, indicating a potential synergistic effect from AEx and cognitive training. The aerobic fitness changes were similar between the exergame and AEx-only groups, indicating that the feasibility of adding cognitive training to AEx concurrently without sacrificing gains in aerobic fitness from AEx. This study shows the flexibility of exergame delivery and its potentially therapeutic effects in persons at risk for Alzheimer's dementia. CLINICAL TRIAL REGISTRATION NUMBER: NCT04311736.

Indexed as

Cognitive DysfunctionExercise TherapyTelerehabilitationAgedAged, 80 and overCognitionExerciseFemaleHumansMaleVideo GamesAlzheimer’s diseaseCardiorespiratory fitnessCognitive functionPhysical activity/exercise

Identifiers

PMID38486359
PMCPMC11138364
OpenAlexW4392858989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.