Evidence map›Paper›PMID 38486039›Full record

ArticleScientific data2024

NuInsSeg: A fully annotated dataset for nuclei instance segmentation in H&E-stained histological images.

Amirreza Mahbod, Christine Polak, Katharina Feldmann, Rumsha Khan, Katharina Gelles, Georg Dorffner, Ramona Woitek, Sepideh Hatamikia, Isabella Ellinger

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  16. NOISe: Nuclei-Aware Osteoclast Instance Segmentation for Mouse-to-Human Domain Transfer.Conference on Computer Vision and Pattern Recognition Workshops. IEEE Computer Society Conference on Computer Vision and Pattern Recognition. Workshops · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amirreza MahbodResearch Center for Medical Image Analysis and Artificial Intelligence, Department of Medicine, Danube Private University, Krems an der Donau, 3500, Austria. amirreza.mahbod@dp-uni.ac.at.ORCID 0000-0001-5042-1442
Christine PolakInstitute for Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, 1090, Austria.
Katharina FeldmannInstitute for Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, 1090, Austria.
Rumsha KhanInstitute for Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, 1090, Austria.
Katharina GellesInstitute for Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, 1090, Austria.
Georg DorffnerInstitute of Artificial Intelligence, Medical University of Vienna, Vienna, 1090, Austria.
Ramona WoitekResearch Center for Medical Image Analysis and Artificial Intelligence, Department of Medicine, Danube Private University, Krems an der Donau, 3500, Austria.
Sepideh HatamikiaResearch Center for Medical Image Analysis and Artificial Intelligence, Department of Medicine, Danube Private University, Krems an der Donau, 3500, Austria.
Isabella EllingerInstitute for Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, 1090, Austria.ORCID 0000-0001-6335-076X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In computational pathology, automatic nuclei instance segmentation plays an essential role in whole slide image analysis. While many computerized approaches have been proposed for this task, supervised deep learning (DL) methods have shown superior segmentation performances compared to classical machine learning and image processing techniques. However, these models need fully annotated datasets for training which is challenging to acquire, especially in the medical domain. In this work, we release one of the biggest fully manually annotated datasets of nuclei in Hematoxylin and Eosin (H&E)-stained histological images, called NuInsSeg. This dataset contains 665 image patches with more than 30,000 manually segmented nuclei from 31 human and mouse organs. Moreover, for the first time, we provide additional ambiguous area masks for the entire dataset. These vague areas represent the parts of the images where precise and deterministic manual annotations are impossible, even for human experts. The dataset and detailed step-by-step instructions to generate related segmentation masks are publicly available on the respective repositories.

Indexed as

Cell NucleusMachine LearningAnimalsHumansImage Processing, Computer-AssistedMiceStaining and Labeling

Identifiers

PMID38486039
PMCPMC10940572

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.